Diffusion-weighted MR imaging of mediastinal lymphadenopathy in children.
Purpose: To assess mediastinal lymphadenopathy in children with diffusion-weighted MR imaging.Materials and Methods: Retrospective analysis of 29 consecutive children (18 boys and 11 girls aged 2-15 years) with mediastinal lymphadenopathy. They underwent single-shot echo planar diffusion-weighted MR...
| Publicado en: | Japanese Journal of Radiology Vol. 33; no. 8; pp. 449 - 455 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Aug2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109624355&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109624355 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18671071 AUCM jtl: Japanese Journal of Radiology issn: 18671071 maglogo: N pubinfo: dt: Aug2015 vid: 33 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109624355 NLM26067466 2013132753 10.1007/s11604-015-0434-1 NLM26067466 109624355 ppf: 449 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Diffusion-weighted MR imaging of mediastinal lymphadenopathy in children. aug: au: Razek, Ahmed Abdel Khalek Abdel Gaballa, Ghada Elashry, Rasha Elkhamary, Sahar Abdel Razek, Ahmed Abdel Khalek affil: Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, DK, 13351, Egypt sug: ab: Purpose: To assess mediastinal lymphadenopathy in children with diffusion-weighted MR imaging.Materials and Methods: Retrospective analysis of 29 consecutive children (18 boys and 11 girls aged 2-15 years) with mediastinal lymphadenopathy. They underwent single-shot echo planar diffusion-weighted MR imaging of the mediastinum with b factors of 0, 300, and 600 s/mm(2). The ADC value of the mediastinal lymph nodes was calculated and correlated with biopsy results; statistical analysis was also performed.Results: The mean ADC value for malignant mediastinal lymphadenopathy (n = 20) (0.99 ± 0.18 × 10(-3) mm(2)/s) was significantly lower (P = 0.001) than that for benign lymphadenopathy (n = 9) (1.35 ± 0.26 × 10(-3) mm(2)/s). There was significant difference between ADC values for non-Hodgkin lymphoma and metastatic nodes (P = 0.04). For differentiating malignant from benign mediastinal lymphadenopathy, the best result was obtained when an ADC value of 1.22 × 10(-3) mm(2)/s was used as a threshold value; area under the curve was 0.861, accuracy 93.1 %, sensitivity 100 %, specificity of 77.8 %, positive predictive value 90.9 %, and negative predictive value of 100 %.Conclusion: Diffusion-weighted MR imaging is a promising non-invasive imaging modality that can be used for differentiation of malignant from benign mediastinal lymphadenopathy in children. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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