Thyroid Imaging Reporting and Data System (TI-RADS): the impact of Quantitative Strain Elastography for better stratification of cancer risks.
Aims: Due to the elevated prevalence of the solid thyroid nodules in a general population, an appropriate selection of cases referred to surgery is of paramount importance. The main aim of our study was to evaluate the performance of the Thyroid Imaging Reporting and Data System (TI-RADS) as a diffe...
| Publicado en: | Medical Ultrasonography Vol. 17; no. 3; pp. 327 - 333 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
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Romanian Society of Ultrasonography in Medicine & Biology
Sep2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109645038&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109645038 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18444172 AX1S jtl: Medical Ultrasonography issn: 18444172 maglogo: N pubinfo: dt: Sep2015 vid: 17 iid: 3 pid: 57537 pub: Romanian Society of Ultrasonography in Medicine & Biology artinfo: ui: 109645038 NLM26343081 2013163404 10.11152/mu.2013.2066.173.dst NLM26343081 109645038 ppf: 327 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Thyroid Imaging Reporting and Data System (TI-RADS): the impact of Quantitative Strain Elastography for better stratification of cancer risks. aug: au: Stoian, Dana Timar, Bogdan Derban, Mihnea Pantea, Stelian Varcus, Florian Craina, Marius Craciunescu, Mihaela sug: ab: Aims: Due to the elevated prevalence of the solid thyroid nodules in a general population, an appropriate selection of cases referred to surgery is of paramount importance. The main aim of our study was to evaluate the performance of the Thyroid Imaging Reporting and Data System (TI-RADS) as a differential diagnosis tool for thyroid nodules.Material and Methods: We evaluated 174 nodules using TI-RADS risk stratification model, using conventional ultrasound and real time elastography parameters and linear multifrequency probe (Hitachi Preirus Machine, Hitachi Inc., Japan). All the nodules were classified using the TI-RADS system according to echogenicity, margins, shapes, calcification, lymph nodes, and increased strain ration. The results were compared with the pathology exam, which was considered the golden standard diagnosis.Results: The prevalence of malignant nodules was 16.7% (29 cases). The differential diagnosis performance regarding the malignant tumor for TI-RADS is appropriate for clinical use, obtaining an area under ROC curve of 0.95761 [0.8424-0.989] 95% confidence interval. Combining TI-RADS 2, 3 and 4A as probably benign and TI-RADS 4B and 5 as probably malignant, the sensitivity, specificity, positive predictive value, and negative predictive value were 97.93%, 86.20%, 97.26% and 89.28% respectively. The overall accuracy of the method was 95.97%.According to the American Association of Clinical Endocrinologists Guidelines, 169 cases required FNAB examination; by applying the TI-RADS scoring system, the necessity for FNAB would decrease to 74 cases.Conclusion: Quantitative strain elastography, as the 6th parameter of TI-RADS system, adds diagnostic power to the risk stratification model. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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