Health-related quality of life among children, young people and adults with esophageal atresia: a review of the literature and recommendations for future research.
Purpose: Esophageal atresia (EA) is a rare congenital malformation requisite of surgical treatment. Survival rates have significantly increased in recent decades, but treated children are at risk of chronic morbidity. This study aims to review the literature on health-related quality of life (HRQOL)...
| Publicado en: | Quality of Life Research Vol. 24; no. 10; pp. 2433 - 2446 |
|---|---|
| Autores principales: | , , , , |
| Formato: | research review Journal Article |
| Publicado: |
Springer Nature
Oct2015
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109647115&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109647115 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09629343 GPQ jtl: Quality of Life Research issn: 09629343 maglogo: N pubinfo: dt: Oct2015 vid: 24 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109647115 NLM25829227 2013165515 10.1007/s11136-015-0975-x NLM25829227 109647115 ppf: 2433 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Health-related quality of life among children, young people and adults with esophageal atresia: a review of the literature and recommendations for future research. aug: au: Dellenmark-Blom, Michaela Chaplin, John Eric Gatzinsky, Vladimir Jönsson, Linus Abrahamson, Kate sug: ab: Purpose: Esophageal atresia (EA) is a rare congenital malformation requisite of surgical treatment. Survival rates have significantly increased in recent decades, but treated children are at risk of chronic morbidity. This study aims to review the literature on health-related quality of life (HRQOL) in patients with EA and describe the questionnaires used.Methods: A literature search was conducted in Pubmed, Cinahl and PsycINFO, from inception to January 2015. A meta-analysis of studies investigating HRQOL in patients with EA compared to healthy references was performed. The effect size was calculated as Cohen's d.Results: Twelve articles (published 1995-2014) describing HRQOL among children, young people and adults were identified. Only European studies were found, and these had variable sample sizes (8-128). Overall HRQOL was reported to be reduced in five of the seven studies that compared overall HRQOL with a healthy reference population. Impaired physical or general health was described in eight articles. In the meta-analysis, eight eligible studies provided 16 estimates of the effect of EA, six of which reached statistical significance for worse HRQOL (p < 0.05). Using Cohen's criteria, the pooled estimate of the effect of EA was small for overall and physical HRQOL, and <0.2 for the mental and social HRQOL components. Altogether, 15 different questionnaires were used, and none were condition specific for EA.Conclusions: Different findings are reported; however, this study suggests that patients with EA may have a reduced HRQOL. Moreover, HRQOL is not adequately measured in this group. Additional research is required. pubtype: Academic Journal doctype: meta analysis research review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|