No influence of CYP2D6*10 genotype and phenotype on the pharmacokinetics of nebivolol in healthy Chinese subjects.
What is known and objective Nebivolol, a clinically important antihypertensive drug, mainly metabolized by cytochrome P450 ( CYP) 2D6, shows wide interindividual variability in pharmacokinetics. The CYP2D6*10 allele (100C>T; rs1065852), present at a high frequency in the Chinese population, is assoc...
| Publicado en: | Journal of Clinical Pharmacy & Therapeutics Vol. 40; no. 5; pp. 561 - 566 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2015
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| Acceso en línea: | Ver este registro en EBSCOhost |