Associations between CYP19A1 polymorphisms, Native American ancestry, and breast cancer risk and mortality: the Breast Cancer Health Disparities Study.

The cytochrome p450 family 19 gene (CYP19A1) encodes for aromatase, which catalyzes the final step in estrogen biosynthesis and conversion of androgens to estrogens. Genetic variation in CYP19A1 is linked to higher circulating estrogen levels and increased aromatase expression. Using data from the B...

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Bibliographic Details
Published in:Cancer Causes & Control Vol. 25; no. 11; pp. 1461 - 1472
Main Authors: Boone, Stephanie D, Baumgartner, Kathy B, Baumgartner, Richard N, Connor, Avonne E, Pinkston, Christina M, Rai, Shesh N, Riley, Elizabeth C, Hines, Lisa M, Giuliano, Anna R, John, Esther M, Stern, Mariana C, Torres-Mejía, Gabriela, Wolff, Roger K, Slattery, Martha L
Format: research Journal Article
Published: Springer Nature Nov2014
Online Access:View this record in EBSCOhost