Inference on differences between classes using cluster-specific contrasts of mixed effects.

The detection of differentially expressed (DE) genes, that is, genes whose expression levels vary between two or more classes representing different experimental conditions (say, diseases), is one of the most commonly studied problems in bioinformatics. For example, the identification of DE genes be...

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Bibliographic Details
Published in:Biostatistics Vol. 16; no. 1; pp. 98 - 113
Main Authors: Ng, Shu Kay, McLachlan, Geoffrey J, Wang, Kui, Nagymanyoki, Zoltan, Liu, Shubai, Ng, Shu-Wing
Format: Journal Article
Published: Oxford University Press / USA Jan2015
Online Access:View this record in EBSCOhost