Profiling cocaine by ATR-FTIR.
In this article, five hundred and thirteen cocaine seizures of the State of Rio Grande do Sul (Brazil) were analyzed by Fourier transform infrared spectroscopy (FT-IR) in the fingerprint region (1800-650 cm(-1)) to profiling and evaluate the pharmaceutical products used as adulterants. Hierarchical...
| Publicado en: | Forensic Science International Vol. 246; pp. 65 - 72 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Elsevier B.V.
Jan2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109688003&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109688003 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03790738 3L0 jtl: Forensic Science International issn: 03790738 maglogo: N pubinfo: dt: Jan2015 vid: 246 pid: 82545 pub: Elsevier B.V. place: Philadelphia, Pennsylvania artinfo: ui: 109688003 NLM25460107 2012840069 10.1016/j.forsciint.2014.11.011 NLM25460107 109688003 ppf: 65 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Profiling cocaine by ATR-FTIR. aug: au: Marcelo, M C A Mariotti, K C Ferrao, M F Ortiz, R S Ferrão, M F affil: Instituto de Química, Universidade Federal do Rio Grande do Sul, Brazil; Instituto Nacional de Ciência e Tecnologia de Bioanalítica, Campinas, SP, Brazil sug: ab: In this article, five hundred and thirteen cocaine seizures of the State of Rio Grande do Sul (Brazil) were analyzed by Fourier transform infrared spectroscopy (FT-IR) in the fingerprint region (1800-650 cm(-1)) to profiling and evaluate the pharmaceutical products used as adulterants. Hierarchical cluster analysis (HCA) and principal component analysis (PCA) were used to identify patterns among the samples whereas partial least square discriminant analysis (PLS-DA) and support vector machines discriminant analysis (SVM-DA) were used to classification the cocaine between base and salt. Spectra of standard solid mixtures of cocaine (salt and base), phenacetin, lidocaine and caffeine were used associated with PCA to predict qualitatively the profile of cocaine seizure. In HCA and PCA, salt and base group were formed correctly. Accordingly with predicted profile of the salt samples, they were majority adulterated with caffeine and lidocaine whereas base cocaine was adulterated only with phenacetin. In the discrimant analysis, all methods have classified the cocaine samples correctly with sensitivity and specificity equal to one between salt and base. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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