MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects.

Objective: In this study we aimed to describe the magnetic resonance imaging (MRI) pattern of the distribution of bone marrow edema (BME) and joint erosion in hands and wrists of patients with systemic lupus erythematosus (SLE) with arthritis in comparison with rheumatoid arthritis (RA) and healthy...

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Publicado en:Skeletal Radiology Vol. 44; no. 2; pp. 261 - 267
Autores principales: Chiara, Tani, Dario, D'aniello, Niccolò, Possemato, Andrea, Delle Sedie, Davide, Caramella, Stefano, Bombardieri, Marta, Mosca, Tani, Chiara, D'Aniello, Dario, Possemato, Niccolò, Delle Sedie, Andrea, Caramella, Davide, Bombardieri, Stefano, Mosca, Marta
Formato: research Journal Article
Publicado: Springer Nature Feb2015
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects.
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          Chiara, Tani
          Dario, D'aniello
          Niccolò, Possemato
          Andrea, Delle Sedie
          Davide, Caramella
          Stefano, Bombardieri
          Marta, Mosca
          Tani, Chiara
          D'Aniello, Dario
          Possemato, Niccolò
          Delle Sedie, Andrea
          Caramella, Davide
          Bombardieri, Stefano
          Mosca, Marta
      sug:
      ab: Objective: In this study we aimed to describe the magnetic resonance imaging (MRI) pattern of the distribution of bone marrow edema (BME) and joint erosion in hands and wrists of patients with systemic lupus erythematosus (SLE) with arthritis in comparison with rheumatoid arthritis (RA) and healthy subjects (H).Methods: SLE patients with arthritis (n = 50), patients with RA (n = 22), and H (n = 48) were enrolled. Every patient underwent a non-dominant hand (2nd-5th metacarpophalangeal joints) and wrist MRI without contrast injection with a low-field extremity dedicated 0.2-Tesla instrument.Results: BME was observed in two SLE patients in the hand (4%) and in 15 in the wrist (13%) versus three (30%), and 14 (63%) RA patients. No BME was found in H. Erosions were observed in the hand in 24 SLE patients (48%), 15 RA patients (68%), and 9 H (18 %); in the wrist, in 41 (82%) SLE, all RA and 47 (97%) H. The cumulative erosive burden in SLE was significantly higher than in H (c = 0.002) but similar to RA patients.Conclusions: Joint involvement of the wrist in SLE is similar to RA and is not as rare as expected, as shown by the comparison with healthy subjects. On the contrary, the involvement of the hand in SLE is significantly lower compared to RA.
      pubtype: Academic Journal
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    language: English
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