Utility of [18 F]FLT-PET to assess treatment response in trastuzumab-resistant and trastuzumab-sensitive HER2-overexpressing human breast cancer xenografts.

Purpose: The objective of this study was to evaluate 3'-deoxy-3'-[(18) F]fluorothymidine ([(18) F]FLT) positron emission tomography (PET) as an early marker of trastuzumab response in HER2-overexpressing xenografts.Procedures: Tumor-to-muscle ratios were compared between both trastuzumab-sensitive a...

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Detalles Bibliográficos

Publicado en:	Molecular Imaging & Biology Vol. 17; no. 1; pp. 119 - 129
Autores principales:	Whisenant, Jennifer G, McIntyre, J Oliver, Peterson, Todd E, Kang, Hakmook, Sánchez, Violeta, Manning, H Charles, Arteaga, Carlos L, Yankeelov, Thomas E
Formato:	Journal Article
Publicado:	Springer Nature Feb2015
Acceso en línea:	Ver este registro en EBSCOhost