Silicone rubber encapsulation for an endoscopically implantable gastrostimulator.
Gastrointestinal stimulator implants have recently shown positive results in treating obesity. However, the implantation currently requires an invasive surgical procedure. Endoscopy could be used to place the gastric stimulator in the stomach, hence avoiding the riskier surgery. The implant then nee...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 53; no. 4; pp. 319 - 330 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Apr2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109710307&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109710307 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Apr2015 vid: 53 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109710307 NLM25559120 2012940759 10.1007/s11517-014-1236-9 NLM25559120 109710307 ppf: 319 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Silicone rubber encapsulation for an endoscopically implantable gastrostimulator. aug: au: Lonys, Laurent Vanhoestenberghe, Anne Julémont, Nicolas Godet, Stéphane Delplancke, Marie-Paule Mathys, Pierre Nonclercq, Antoine sug: ab: Gastrointestinal stimulator implants have recently shown positive results in treating obesity. However, the implantation currently requires an invasive surgical procedure. Endoscopy could be used to place the gastric stimulator in the stomach, hence avoiding the riskier surgery. The implant then needs to go through the oesophagus and be located inside the stomach, which imposes new design constraints, such as miniaturization and protecting the electronic circuit against the highly acidic environment of the stomach. We propose to protect the implant by encapsulation with silicone rubber. This paper lists the advantages of this method compared to the more usual approach of a hermetic enclosure and then presents a method to evaluate the underwater adhesive stability of six adhesive/substrate couples, using repeated lap-shear tests and an elevated temperature to accelerate the ageing process. The results for different adhesive/substrate couples tested, presented on probability plots, show that FR4 and alumina substrates with MED4-4220 silicone rubber are suitable for a first implantable prototype. We then compare these with the predicted lifetimes of bonds between historical standard silicone rubber DC3140 and different substrates and describe the encapsulation of our gastrostimulator. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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