Magnetic resonance elastography and acoustic radiation force impulse for staging hepatic fibrosis: a meta-analysis.
Purpose: Elastography is a non-invasive method to quantify fibrosis based on tissue mechanical properties. We performed a meta-analysis to assess the diagnostic accuracy of two such techniques: Acoustic Radiation Force Impulse Imaging (ARFI) or Magnetic Resonance Elastography (MRE) for staging hepat...
| Publicado en: | Abdominal Imaging Vol. 40; no. 4; pp. 818 - 835 |
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| Autores principales: | , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Apr2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109714313&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109714313 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09428925 O52 jtl: Abdominal Imaging issn: 09428925 maglogo: N pubinfo: dt: Apr2015 vid: 40 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109714313 NLM24711064 2012950400 10.1007/s00261-014-0137-6 NLM24711064 109714313 ppf: 818 ppct: 17 formats: fmt: @attributes: type: P tig: atl: Magnetic resonance elastography and acoustic radiation force impulse for staging hepatic fibrosis: a meta-analysis. aug: au: Guo, Yang Parthasarathy, Sudharshan Goyal, Preeya McCarthy, Robert J Larson, Andrew C Miller, Frank H sug: ab: Purpose: Elastography is a non-invasive method to quantify fibrosis based on tissue mechanical properties. We performed a meta-analysis to assess the diagnostic accuracy of two such techniques: Acoustic Radiation Force Impulse Imaging (ARFI) or Magnetic Resonance Elastography (MRE) for staging hepatic fibrosis.Materials and Methods: Literature databases were searched until June 2013. Inclusion criteria were evaluation of MRE or ARFI, liver biopsy, and reported sensitivity and specificity. A random effects model was used to combine sensitivity and specificity, from which positive (LR+) and negative (LR-) likelihood ratios, diagnostic odds ratios, and area under receiver operating characteristics curve (AUROC) were derived. Differences between MRE and ARFI were compared with t tests (P < 0.05 considered significant).Results: Eleven MRE studies including 982 patients and fifteen ARFI studies including 2,128 patients were selected. AUROC for MRE staging fibrosis were 0.94, 0.97, 0.96, and 0.97 for F1-F4, respectively, whereas AUROC for ARFI staging were 0.82, 0.85, 0.94, and 0.94 for F1-F4, respectively. Significance was found in AUROC between MRE and ARFI for the diagnosis of stage 1 and 2 fibrosis.Conclusion: MRE is more accurate than ARFI with a higher combination of sensitivity, specificity, LR, and AUROC particularly in diagnosing early stages of hepatic fibrosis. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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