Application of a two-stage fuzzy neural network to a prostate cancer prognosis system.
Objective: This study intends to develop a two-stage fuzzy neural network (FNN) for prognoses of prostate cancer. Methods: Due to the difficulty of making prognoses of prostate cancer, this study proposes a two-stage FNN for prediction. The initial membership function parameters of FNN are determine...
| Published in: | Artificial Intelligence in Medicine Vol. 63; no. 2; pp. 119 - 134 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Published: |
Elsevier B.V.
Feb2015
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109724664&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109724664 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09333657 3HY jtl: Artificial Intelligence in Medicine issn: 09333657 maglogo: N pubinfo: dt: Feb2015 vid: 63 iid: 2 pid: 1004 pub: Elsevier B.V. artinfo: ui: 109724664 NLM25576196 2012975983 10.1016/j.artmed.2014.12.008 NLM25576196 109724664 ppf: 119 ppct: 15 formats: tig: atl: Application of a two-stage fuzzy neural network to a prostate cancer prognosis system. aug: au: Kuo, Ren-Jieh Huang, Man-Hsin Cheng, Wei-Che Lin, Chih-Chieh Wu, Yung-Hung sug: ab: Objective: This study intends to develop a two-stage fuzzy neural network (FNN) for prognoses of prostate cancer. Methods: Due to the difficulty of making prognoses of prostate cancer, this study proposes a two-stage FNN for prediction. The initial membership function parameters of FNN are determined by cluster analysis. Then, an integration of the optimization version of an artificial immune network (Opt-aiNET) and a particle swarm optimization (PSO) algorithm is developed to investigate the relationship between the inputs and outputs. Results: The evaluation results for three benchmark functions show that the proposed two-stage FNN has better performance than the other algorithms. In addition, model evaluation results indicate that the proposed algorithm really can predict prognoses of prostate cancer more accurately. Conclusions: The proposed two-stage FNN is able to learn the relationship between the clinical features and the prognosis of prostate cancer. Once the clinical data are known, the prognosis of prostate cancer patient can be predicted. Furthermore, unlike artificial neural networks, it is much easier to interpret the training results of the proposed network since they are in the form of fuzzy IF-THEN rules. These rules are very important for medical doctors. This can dramatically assist medical doctors to make decisions. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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