Image quality of low mA CT pulmonary angiography reconstructed with model based iterative reconstruction versus standard CT pulmonary angiography reconstructed with filtered back projection: an equivalency trial.

Objective: To determine whether CT pulmonary angiography (CTPA) using low mA setting reconstructed with model-based iterative reconstruction (MBIR) is equivalent to routine CTPA reconstructed with filtered back projection (FBP).Methods: This prospective study was approved by the institutional review...

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Publicado en:European Radiology Vol. 25; no. 6; pp. 1665 - 1672
Autores principales: Montet, Xavier, Hachulla, Anne-Lise, Neroladaki, Angeliki, Lador, Frederic, Rochat, Thierry, Botsikas, Diomidis, Becker, Christoph D
Formato: research Journal Article
Publicado: Springer Nature Jun2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2015
      vid: 25
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      pub: Springer Nature
      place: New York, New York
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        atl: Image quality of low mA CT pulmonary angiography reconstructed with model based iterative reconstruction versus standard CT pulmonary angiography reconstructed with filtered back projection: an equivalency trial.
      aug:
        au:
          Montet, Xavier
          Hachulla, Anne-Lise
          Neroladaki, Angeliki
          Lador, Frederic
          Rochat, Thierry
          Botsikas, Diomidis
          Becker, Christoph D
      sug:
        subj:
          Tomography, X-Ray Computed Methods
          Lung Blood Supply
          Lung
          Image Processing, Computer Assisted Methods
          Angiography Methods
          Prospective Studies
          Female
          Human
          Sensitivity and Specificity
          Male
          Middle Age
          Radiographic Image Interpretation, Computer-Assisted Methods
          Models, Theoretical
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Ferrans and Powers Quality of Life Index
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: To determine whether CT pulmonary angiography (CTPA) using low mA setting reconstructed with model-based iterative reconstruction (MBIR) is equivalent to routine CTPA reconstructed with filtered back projection (FBP).Methods: This prospective study was approved by the institutional review board and patients provided written informed consent. Eighty-two patients were examined with a low mA MBIR-CTPA (100 kV, 20 mA) and 82 patients with a standard FBP-CTPA (100 kV, 250 mA). Region of interests were drawn in nine pulmonary vessels; signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. A five-point scale was used to subjectively evaluate the image quality of FBP-CTPA and low mA MBIR-CTPA.Results: Compared to routine FBP-CTPA, low mA MBIR-CTPA showed no differences in the attenuation measured in nine pulmonary vessels, higher SNR (56 ± 19 vs 43 ± 20, p < 0.0001) and higher CNR (50 ± 17 vs 38 ± 18, p < 0.0001) despite a dose reduction of 93 % (p < 0.0001). The subjective image quality of low mA MBIR-CTPA was quoted as diagnostic in 98 % of the cases for patient with body mass index less than 30 kg/m(2).Conclusion: Low mA MBIR-CTPA is equivalent to routine FBP-CTPA and allows a significant dose reduction while improving SNR and CNR in the pulmonary vessels, as compared with routine FBP-CTPA.Key Points: • Low mA MBIR-CTPA is equivalent to routine FBP-CTPA. • MBIR-CTPA may be achieved with drastic (93 %) dose reduction. • Low mA MBIR-CTPA should be studied in the setting of suspected PE.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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