Comparison of four software packages for CT lung volumetry in healthy individuals.
Objectives: To compare CT lung volumetry (CTLV) measurements provided by different software packages, and to provide normative data for lung densitometric measurements in healthy individuals.Methods: This retrospective study included 51 chest CTs of 17 volunteers (eight men and nine women; mean age,...
| Publicado en: | European Radiology Vol. 25; no. 6; pp. 1588 - 1598 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jun2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109732012&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109732012 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jun2015 vid: 25 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109732012 NLM25576226 2012995365 10.1007/s00330-014-3557-3 NLM25576226 109732012 ppf: 1588 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Comparison of four software packages for CT lung volumetry in healthy individuals. aug: au: Nemec, Stefan F Molinari, Francesco Dufresne, Valerie Gosset, Natacha Silva, Mario Bankier, Alexander A sug: subj: Lung Software Tomography, X-Ray Computed Methods Total Lung Capacity Male Young Adult Retrospective Design Human Reproducibility of Results Female Densitometry Adult Analysis of Variance Lung Volume Measurements Methods Reference Values Spirometry Validation Studies Comparative Studies Evaluation Research Multicenter Studies Clinical Assessment Tools Scales Adult: 19-44 years Male Female ab: Objectives: To compare CT lung volumetry (CTLV) measurements provided by different software packages, and to provide normative data for lung densitometric measurements in healthy individuals.Methods: This retrospective study included 51 chest CTs of 17 volunteers (eight men and nine women; mean age, 30 ± 6 years), who underwent spirometrically monitored CT at total lung capacity (TLC), functional residual capacity (FRC), and mean inspiratory capacity (MIC). Volumetric differences assessed by four commercial software packages were compared with analysis of variance (ANOVA) for repeated measurements and benchmarked against the threshold for acceptable variability between spirometric measurements. Mean lung density (MLD) and parenchymal heterogeneity (MLD-SD) were also compared with ANOVA.Results: Volumetric differences ranged from 12 to 213 ml (0.20 % to 6.45 %). Although 16/18 comparisons (among four software packages at TLC, MIC, and FRC) were statistically significant (P < 0.001 to P = 0.004), only 3/18 comparisons, one at MIC and two at FRC, exceeded the spirometry variability threshold. MLD and MLD-SD significantly increased with decreasing volumes, and were significantly larger in lower compared to upper lobes (P < 0.001).Conclusions: Lung volumetric differences provided by different software packages are small. These differences should not be interpreted based on statistical significance alone, but together with absolute volumetric differences.Key Points: • Volumetric differences, assessed by different CTLV software, are small but statistically significant. • Volumetric differences are smaller at TLC than at MIC and FRC. • Volumetric differences rarely exceed spirometric repeatability thresholds at MIC and FRC. • Differences between CTLV measurements should be interpreted based on comparison of absolute differences. • MLD increases with decreasing volumes, and is larger in lower compared to upper lobes. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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