Efficient stereological approaches for the volumetry of a normal or enlarged spleen from MDCT images.
Objectives: To introduce efficient stereological approaches for estimating the volume of a normal or enlarged spleen from MDCT.Methods: All study participants underwent an abdominal MDCT. The first group included 20 consecutive patients with splenomegaly and the second group consisted of 20 subjects...
| Publicado en: | European Radiology Vol. 25; no. 6; pp. 1761 - 1768 |
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| Autores principales: | , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jun2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109732025&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109732025 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jun2015 vid: 25 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109732025 NLM25578498 2012995378 10.1007/s00330-014-3561-7 NLM25578498 109732025 ppf: 1761 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Efficient stereological approaches for the volumetry of a normal or enlarged spleen from MDCT images. aug: au: Mazonakis, Michalis Stratakis, John Damilakis, John sug: subj: Splenomegaly Pathology Spleen Anatomy and Histology Multidetector Computed Tomography Methods Reference Values Spleen Sensitivity and Specificity Male Middle Age Human Body Weights and Measures Aged Multidetector Computed Tomography Standards Splenomegaly Female Validation Studies Comparative Studies Evaluation Research Multicenter Studies Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Objectives: To introduce efficient stereological approaches for estimating the volume of a normal or enlarged spleen from MDCT.Methods: All study participants underwent an abdominal MDCT. The first group included 20 consecutive patients with splenomegaly and the second group consisted of 20 subjects with a normal spleen. Splenic volume estimations were performed using the stereological point counting method. Stereological assessments were optimized using the systematic slice sampling procedure. Planimetric measurements based on manual tracing of splenic boundaries on each slice were taken as reference values.Results: Stereological analysis using five to eight systematically sampled slices provided enlarged splenic volume estimations with a mean precision of 4.9 ± 1.0 % in a mean time of 2.3 ± 0.4 min. A similar measurement duration and error was observed for normal splenic volume assessment using four to seven systematically selected slices. These stereological approaches slightly but insignificantly overestimated the volume of a normal and enlarged spleen compared to planimetry (P > 0.05) with a mean difference of -1.3 ± 4.3 % and -2.7 ± 5.2 %, respectively. The two methods were highly correlated (r ≥ 0.96). The variability of repeated stereological estimations was below 3.8 %.Conclusions: The proposed stereological approaches enable the rapid, reproducible, and accurate splenic volume estimation from MDCT data in patients with or without splenomegaly.Key Points: • New efficient stereological approaches are proposed for spleen volumetry from MDCT • These volumetric approaches are applicable in patients with or without splenomegaly • Stereological splenic volume estimations from MDCT are rapid, reproducible, and accurate. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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