Information of prostate biopsy positive core: does it affect MR detection of prostate cancer on using 3T-MRI?

Objective: We assessed which information from a prostate biopsy had the strongest relationship with prostate cancer detection by 3T-MRI.Materials and Methods: Sixty-one consecutive patients with biopsy-proven prostate cancer who underwent 3T-MRI before biopsy were enrolled in this retrospective stud...

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Published in:Japanese Journal of Radiology Vol. 33; no. 5; pp. 246 - 253
Main Authors: Yoshida, Rika, Kaji, Yasushi, Tamaki, Yukihisa, Katsube, Takashi, Kitagaki, Hajime, Kanbara, Tsunehito, Kamai, Takao
Format: Journal Article
Published: Springer Nature May2015
Online Access:View this record in EBSCOhost
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        atl: Information of prostate biopsy positive core: does it affect MR detection of prostate cancer on using 3T-MRI?
      aug:
        au:
          Yoshida, Rika
          Kaji, Yasushi
          Tamaki, Yukihisa
          Katsube, Takashi
          Kitagaki, Hajime
          Kanbara, Tsunehito
          Kamai, Takao
      sug:
      ab: Objective: We assessed which information from a prostate biopsy had the strongest relationship with prostate cancer detection by 3T-MRI.Materials and Methods: Sixty-one consecutive patients with biopsy-proven prostate cancer who underwent 3T-MRI before biopsy were enrolled in this retrospective study. Two radiologists independently reviewed T2-weighted and diffusion-weighted images. When the cancer lesions were revealed by biopsy and MRI depicted them at corresponding sites, we classified these lesions as MRI-detectable cancer. If the cancer lesions were revealed by biopsy, but any cancers had not been detected, we classified these lesions as MRI-undetectable cancer. We compared the Gleason score (GS), cancer ratio (CaR) and cancer length (CaL) from core biopsies between the two groups.the Results: GS, CaR and CaL differed significantly between the MRI-detectable group (N = 70), and the MRI-undetectable group (N = 73). 3T-MRI could detect cancer cores with a sensitivity of 90.5% in cores with CaR ≥ 60%, and with a sensitivity of 81.8% in those with CaL ≥ 5 mm. Receiver operating characteristic analysis showed that CaR (P = 0.006) and CaL (P = 0.010) significantly associated with the prostate cancer detection using MRI rather than GS.Conclusion: CaR and CaL from the core biopsies showed a stronger relationship to detection of the prostate cancer on 3T-MRI than the GS did.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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