Improvement of diagnostic confidence for detection of multiple myeloma involvement of the ribs by a new CT software generating rib unfolded images: Comparison with 5- and 1-mm axial images.
Objective: To investigate the performance of a new CT software generating rib unfolded images for improved detection of rib osteolyses in patients with multiple myeloma.Materials and Methods: One hundred sixteen patients who underwent whole-body reduced-dose multidetector computed tomography (WBRD-M...
| Publicado en: | Skeletal Radiology Vol. 44; no. 7; pp. 971 - 980 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jul2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109737078&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109737078 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03642348 O14 jtl: Skeletal Radiology issn: 03642348 maglogo: N pubinfo: dt: Jul2015 vid: 44 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109737078 NLM25833276 2013011532 10.1007/s00256-015-2131-7 NLM25833276 109737078 ppf: 971 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Improvement of diagnostic confidence for detection of multiple myeloma involvement of the ribs by a new CT software generating rib unfolded images: Comparison with 5- and 1-mm axial images. aug: au: Homann, Georg Weisel, Katja Mustafa, Deedar Farhad Ditt, Hendrik Nikolaou, Konstantin Horger, Marius sug: ab: Objective: To investigate the performance of a new CT software generating rib unfolded images for improved detection of rib osteolyses in patients with multiple myeloma.Materials and Methods: One hundred sixteen patients who underwent whole-body reduced-dose multidetector computed tomography (WBRD-MDCT) for multiple myeloma diagnosis and during follow-up were retrospectively evaluated. Nonenhanced CT scans with 5- and 1-mm slice thickness were interpreted by two readers with focus on detection of rib involvement (location, number, fracture). Image analysis of "unfolded," 1-mm-based CT rib images was subsequently undertaken. We classified the number of lytic bone lesions into 0, 1, 2, <5, <10 and ≥10. For all three data sets the reading time was registered.Results: An approximated sum of 6,727 myeloma-related rib lesions was found. On a patient-based analysis, CT (5 mm), CT (1 mm) and CT (1 mm "unfolded rib") yielded a sensitivity, specificity and accuracy of 79.7/94.7/87.1, 88.1/93/90.5 and 98.3/96.5/97.4, respectively. In a lesion-based analysis, the sensitivity, specificity and accuracy of the three evaluations were 69.7/87.2/70.5, 79.8/55.9/78 and 96.5/89.7/96.1. Mean reading time for 5 mm/1 mm axial images and unfolded images was 178.7/215.1/90.8 s, respectively.Conclusion: The generation of "unfolded rib" images improves detection of rib involvement in patients with multiple myeloma and significantly reduces reading time. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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