Comparison of manual and semi-automatic measuring techniques in MSCT scans of patients with lymphoma: a multicentre study.

Objectives: Multicentre evaluation of the precision of semi-automatic 2D/3D measurements in comparison to manual, linear measurements of lymph nodes regarding their inter-observer variability in multi-slice CT (MSCT) of patients with lymphoma.Methods: MSCT data of 63 patients were interpreted before...

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Publicado en:European Radiology Vol. 24; no. 11; pp. 2709 - 2719
Autores principales: Höink, A J, Weßling, J, Koch, R, Schülke, C, Kohlhase, N, Wassenaar, L, Mesters, R M, D'Anastasi, M, Fabel, M, Wulff, A, Pinto Dos Santos, D, Kießling, A, Graser, A, Dicken, V, Karpitschka, M, Bornemann, L, Heindel, W, Buerke, B
Formato: research Journal Article
Publicado: Springer Nature Nov2014
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Comparison of manual and semi-automatic measuring techniques in MSCT scans of patients with lymphoma: a multicentre study.
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          Höink, A J
          Weßling, J
          Koch, R
          Schülke, C
          Kohlhase, N
          Wassenaar, L
          Mesters, R M
          D'Anastasi, M
          Fabel, M
          Wulff, A
          Pinto Dos Santos, D
          Kießling, A
          Graser, A
          Dicken, V
          Karpitschka, M
          Bornemann, L
          Heindel, W
          Buerke, B
        affil: Department of Clinical Radiology, University Hospital Münster, Albert-Schweitzer-Campus 1 (Building: A1), 48149, Münster, Germany, anna.hoeink@ukmuenster.de.
      sug:
        subj:
          Lymph Nodes Radiography
          Lymphoma Radiography
          Multidetector Computed Tomography Methods
          Adult
          Aged
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          Female
          Human
          Male
          Middle Age
          ROC Curve
          Reproducibility of Results
          Young Adult
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objectives: Multicentre evaluation of the precision of semi-automatic 2D/3D measurements in comparison to manual, linear measurements of lymph nodes regarding their inter-observer variability in multi-slice CT (MSCT) of patients with lymphoma.Methods: MSCT data of 63 patients were interpreted before and after chemotherapy by one/two radiologists in five university hospitals. In 307 lymph nodes, short (SAD)/long (LAD) axis diameter and WHO area were determined manually and semi-automatically. Volume was solely calculated semi-automatically. To determine the precision of the individual parameters, a mean was calculated for every lymph node/parameter. Deviation of the measured parameters from this mean was evaluated separately. Statistical analysis entailed intraclass correlation coefficients (ICC) and Kruskal-Wallis tests.Results: Median relative deviations of semi-automatic parameters were smaller than deviations of manually assessed parameters, e.g. semi-automatic SAD 5.3 vs. manual 6.5 %. Median variations among different study sites were smaller if the measurement was conducted semi-automatically, e. g. manual LAD 5.7/4.2 % vs. semi-automatic 3.4/3.4 %. Semi-automatic volumetry was superior to the other parameters (2.8 %).Conclusions: Semi-automatic determination of different lymph node parameters is (compared to manually assessed parameters) associated with a slightly greater precision and a marginally lower inter-observer variability. These results are with regard to the increasing mobility of patients among different medical centres and in relation to the quality management of multicentre trials of importance.Key Points: • In a multicentre setting, semi-automatic measurements are more accurate than manual assessments. • Lymph node volumetry outperforms all other semi-automatically and manually performed measurements. • Use of semi-automatic lymph node analyses can reduce the inter-observer variability.
      pubtype: Academic Journal
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        research
        Journal Article
      ougenre: Article
    language: English
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