Papillary breast lesions on contrast-enhanced ultrasound: morphological enhancement patterns and diagnostic strategy.
Objectives: To identify features which determine the papillary nature of breast lesions by contrast-enhanced ultrasound (CEUS) based on morphological and pathological correlations, and predict which papillomas are malignant.Methods: A retrospective review of 47 papillary lesions and 51 hypervascular...
| Publicado en: | European Radiology Vol. 24; no. 12; pp. 3178 - 3191 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Dec2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109764121&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109764121 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Dec2014 vid: 24 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109764121 NLM25149297 2012798354 10.1007/s00330-014-3375-7 NLM25149297 109764121 ppf: 3178 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Papillary breast lesions on contrast-enhanced ultrasound: morphological enhancement patterns and diagnostic strategy. aug: au: Xia, Han-Sheng Wang, Xi Ding, Hong Wen, Jie-Xian Fan, Pei-Li Wang, Wen-Ping affil: Department of Ultrasound, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China. sug: subj: Breast Neoplasms Ultrasonography Carcinoma, Papillary Ultrasonography Contrast Media Diagnostic Use Image Enhancement Methods Papilloma Ultrasonography Ultrasonography, Doppler, Color Methods Ultrasonography Methods Adult Aged Aged, 80 and Over Biopsy Breast Neoplasms Pathology Carcinoma, Papillary Pathology Diagnosis, Differential Female Prospective Studies Human Middle Age Papilloma Pathology Reproducibility of Results Retrospective Design Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female ab: Objectives: To identify features which determine the papillary nature of breast lesions by contrast-enhanced ultrasound (CEUS) based on morphological and pathological correlations, and predict which papillomas are malignant.Methods: A retrospective review of 47 papillary lesions and 51 hypervascular benign abnormalities was performed. Enhancement patterns and diagnostic performance of CEUS were assessed.Results: The most frequent finding in papillary lesions was perilesional linear ductal enhancement (87.2%) followed by heterogeneous enhancement (80.9%), and the presence of perfusion defects (66%). Among all CEUS morphological descriptors, a perilesional linear ductal enhancement pattern was the most effective feature to discriminate between papillary and hypervascular benign lesions. Using this criterion, the positive and negative predictive value for papilloma were 100% and 89.5%, respectively. A perilesional linear ductal pattern correlated with a ductal origin. The distinctive features associated with atypical or malignant papillomas were non-confluent enhancement, late overall wash-out, the presence of regional perfusion defect, clumped vascular pattern, and the presence of peripheral radial or penetrating vessels. The sensitivity, specificity, and positive and negative predictive values for predicting malignancy were 91.7%, 82.6%, 84.6% and 90.5%, respectively.Conclusions: CEUS provided characteristic enhancement patterns which could be helpful for identifying papillary lesions and for predicting potentially malignant papillomas.Key Points: Papillary breast lesions display a characteristic appearance on CEUS. Adding CEUS to conventional US helps identify the papillary nature of papillomas. CEUS may be helpful for predicting potential malignancies among papillomas. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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