Preclinical imaging evaluation of novel TSPO-PET ligand 2-(5,7-Diethyl-2-(4-(2-[(18)F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([ (18)F]VUIIS1008) in glioma.

Purpose: Translocator protein (TSPO) concentrations are elevated in glioma, suggesting a role for TSPO positron emission tomography (PET) imaging in this setting. In preclinical PET studies, we evaluated a novel, high-affinity TSPO PET ligand, [(18)F]VUIIS1008, in healthy mice and glioma-bearing rat...

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Publicado en:	Molecular Imaging & Biology Vol. 16; no. 6; pp. 813 - 821
Autores principales:	Tang, Dewei, Nickels, Michael L, Tantawy, M Noor, Buck, Jason R, Manning, H Charles
Formato:	research Journal Article
Publicado:	Springer Nature Dec2014
Acceso en línea:	Ver este registro en EBSCOhost