Noninvasive reporter gene imaging of human Oct4 (pluripotency) dynamics during the differentiation of embryonic stem cells in living subjects.

Purpose: Human pluripotency gene networks (PGNs), controlled in part by Oct4, are central to understanding pluripotent stem cells, but current fluorescent reporter genes (RGs) preclude noninvasive assessment of Oct4 dynamics in living subjects.Procedures: To assess Oc4 activity noninvasively, we eng...

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Publicado en:	Molecular Imaging & Biology Vol. 16; no. 6; pp. 865 - 877
Autores principales:	Ahn, Byeong-Cheol, Parashurama, Natesh, Patel, Manish, Ziv, Keren, Bhaumik, Srabani, Yaghoubi, Shahriar Shah, Paulmurugan, Ramasamy, Gambhir, Sanjiv Sam
Formato:	research Journal Article
Publicado:	Springer Nature Dec2014
Acceso en línea:	Ver este registro en EBSCOhost