Computed tomographic characteristics of interval and post screen carcinomas in lung cancer screening.
Objectives: To analyse computed tomography (CT) findings of interval and post-screen carcinomas in lung cancer screening.Methods: Consecutive interval and post-screen carcinomas from the Dutch-Belgium lung cancer screening trial were included. The prior screening and the diagnostic chest CT were rev...
| Publicado en: | European Radiology Vol. 25; no. 1; pp. 81 - 89 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jan2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109769007&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109769007 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jan2015 vid: 25 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109769007 NLM25187382 2012825791 10.1007/s00330-014-3394-4 NLM25187382 109769007 ppf: 81 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Computed tomographic characteristics of interval and post screen carcinomas in lung cancer screening. aug: au: Scholten, Ernst Th Horeweg, Nanda de Koning, Harry J Vliegenthart, Rozemarijn Oudkerk, Matthijs Mali, Willem P Th M de Jong, Pim A affil: Department of Radiology, University Medical Centre, Utrecht, The Netherlands, ethscholten@quicknet.nl. sug: subj: Carcinoma Radiography Lung Neoplasms Radiography Aged Belgium Bronchial Neoplasms Radiography Diagnosis, Delayed Early Detection of Cancer Methods Female Human Neoplasm Metastasis Male Middle Age Multidetector Computed Tomography Standards Netherlands Observer Bias Pleural Effusion Etiology Retrospective Design Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objectives: To analyse computed tomography (CT) findings of interval and post-screen carcinomas in lung cancer screening.Methods: Consecutive interval and post-screen carcinomas from the Dutch-Belgium lung cancer screening trial were included. The prior screening and the diagnostic chest CT were reviewed by two experienced radiologists in consensus with knowledge of the tumour location on the diagnostic CT.Results: Sixty-one participants (53 men) were diagnosed with an interval or post-screen carcinoma. Twenty-two (36%) were in retrospect visible on the prior screening CT. Detection error occurred in 20 cancers and interpretation error in two cancers. Errors involved intrabronchial tumour (n = 5), bulla with wall thickening (n = 5), lymphadenopathy (n = 3), pleural effusion (n = 1) and intraparenchymal solid nodules (n = 8). These were missed because of a broad pleural attachment (n = 4), extensive reticulation surrounding a nodule (n = 1) and extensive scarring (n = 1). No definite explanation other than human error was found in two cases. None of the interval or post-screen carcinomas involved a subsolid nodule.Conclusions: Interval or post-screen carcinomas that were visible in retrospect were mostly due to detection errors of solid nodules, bulla wall thickening or endobronchial lesions. Interval or post-screen carcinomas without explanation other than human errors are rare.Key Points: • 22% of missed carcinomas originally presented as bulla wall thickening on CT. • 22% of missed carcinomas originally presented as endobronchial lesions on CT. • All malignant endobronchial lesions presented as interval carcinomas. • In the NELSON trial subsolid nodules were not a source of missed carcinomas. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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