Assessing the complexity of short-term heartbeat interval series by distribution entropy.

Complexity of heartbeat interval series is typically measured by entropy. Recent studies have found that sample entropy (SampEn) or fuzzy entropy (FuzzyEn) quantifies essentially the randomness, which may not be uniformly identical to complexity. Additionally, these entropy measures are heavily depe...

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Publicado en:Medical & Biological Engineering & Computing Vol. 53; no. 1; pp. 77 - 88
Autores principales: Li, Peng, Liu, Chengyu, Li, Ke, Zheng, Dingchang, Liu, Changchun, Hou, Yinglong
Formato: research Journal Article
Publicado: Springer Nature Jan2015
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Assessing the complexity of short-term heartbeat interval series by distribution entropy.
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          Li, Peng
          Liu, Chengyu
          Li, Ke
          Zheng, Dingchang
          Liu, Changchun
          Hou, Yinglong
      sug:
        subj:
          Physics
          Heart Rate Physiology
          Adult
          Aged
          Aged, 80 and Over
          Algorithms
          Computer Simulation
          Female
          Human
          Male
          Statistics
          Young Adult
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Female
          Male
      ab: Complexity of heartbeat interval series is typically measured by entropy. Recent studies have found that sample entropy (SampEn) or fuzzy entropy (FuzzyEn) quantifies essentially the randomness, which may not be uniformly identical to complexity. Additionally, these entropy measures are heavily dependent on the predetermined parameters and confined to data length. Aiming at improving the robustness of complexity assessment for short-term RR interval series, this study developed a novel measure--distribution entropy (DistEn). The DistEn took full advantage of the inherent information underlying the vector-to-vector distances in the state space by probability density estimation. Performances of DistEn were examined by theoretical data and experimental short-term RR interval series. Results showed that DistEn correctly ranked the complexity of simulated chaotic series and Gaussian noise series. The DistEn had relatively lower sensitivity to the predetermined parameters and showed stability even for quantifying the complexity of extremely short series. Analysis further showed that the DistEn indicated the loss of complexity in both healthy aging and heart failure patients (both p < 0.01), whereas neither the SampEn nor the FuzzyEn achieved comparable results (all p ≥ 0.05). This study suggested that the DistEn would be a promising measure for prompt clinical examination of cardiovascular function.
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    language: English
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