Differentiation of BIRADS-4 small breast lesions via Multimodal Ultrasound Tomography.
Purpose: To demonstrate the use of a new 3D diagnostic imaging technology, termed Multimodal Ultrasonic Tomography (MUT), for the detection of solid breast lesions < 15 mm in maximum dimension.Methods and Materials: 3D MUT imaging was performed on 71 volunteers presenting BIRADS-4 nodules, asymmetri...
| Publicado en: | European Radiology Vol. 25; no. 2; pp. 410 - 419 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Feb2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109774205&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109774205 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Feb2015 vid: 25 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109774205 NLM25218763 2012873597 10.1007/s00330-014-3415-3 NLM25218763 109774205 ppf: 410 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Differentiation of BIRADS-4 small breast lesions via Multimodal Ultrasound Tomography. aug: au: Zografos, G Liakou, P Koulocheri, D Liovarou, I Sofras, M Hadjiagapis, S Orme, M Marmarelis, V affil: Breast Unit, University of Athens School of Medicine, Athens, Greece, gzografo@med.uoa.gr. sug: subj: Breast Neoplasms Ultrasonography Imaging, Three-Dimensional Diagnostic Imaging Methods Neoplasm Staging Methods Ultrasonography Methods Biopsy Breast Neoplasms Pathology Diagnosis, Differential Female Human Reproducibility of Results Retrospective Design Female ab: Purpose: To demonstrate the use of a new 3D diagnostic imaging technology, termed Multimodal Ultrasonic Tomography (MUT), for the detection of solid breast lesions < 15 mm in maximum dimension.Methods and Materials: 3D MUT imaging was performed on 71 volunteers presenting BIRADS-4 nodules, asymmetrical densities, and architectural distortions in X-ray mammograms, who subsequently underwent biopsy. MUT involved D tomographic imaging of the pendulant breast in a water bath using transmission ultrasound and constructed multimodal images corresponding to refractivity and frequency-dependent attenuation (calibrated relative to water). The multimodal images were fused into composite images and a composite index (CI) was calculated and used for diagnostic purposes. The composite images were evaluated against results of histopathology on biopsy specimens.Results: Histopathology revealed 22 malignant and 49 benign lesions. The pixels of 22 malignant lesions exhibited high values in both refractivity and attenuation, resulting in CI values > 1. In contrast, 99.9% of benign lesions and normal tissue pixels exhibited lower values of at least one of the attributes measured, corresponding to CI values < 1.Conclusions: MUT imaging appears to differentiate small malignant solid breast lesions as exhibiting CI values >1, while benign lesions or normal breast tissues exhibit CI values <1.Key Points: • MUT was able to detect all 22 biopsy-confirmed malignant lesions. • MUT was able to differentiate the malignant from the benign lesions. • Additional MUT detections outside the biopsy area must be evaluated prospectively. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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