The influence of alignment-free sequence representations on the semi-supervised classification of class C G protein-coupled receptors: semi-supervised classification of class C GPCRs.

G protein-coupled receptors (GPCRs) are integral cell membrane proteins of relevance for pharmacology. The tertiary structure of the transmembrane domain, a gate to the study of protein functionality, is unknown for almost all members of class C GPCRs, which are the target of the current study. As a...

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Bibliographic Details
Published in:Medical & Biological Engineering & Computing Vol. 53; no. 2; pp. 137 - 150
Main Authors: Cruz-Barbosa, Raúl, Vellido, Alfredo, Giraldo, Jesús
Format: research Journal Article
Published: Springer Nature Feb2015
Online Access:View this record in EBSCOhost