Does diffusion MRI tell us anything about the white matter? An overview of methods and pitfalls.

One key pitfall in diffusion magnetic resonance imaging (dMRI) clinical neuroimaging research is the challenge of understanding and interpreting the results of a complex analysis pipeline. The sophisticated algorithms employed by the analysis software, combined with the relatively non-specific natur...

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Publicado en:Schizophrenia Research Vol. 161; no. 1; pp. 133 - 142
Autores principales: O'Donnell, Lauren J, Pasternak, Ofer
Formato: review Journal Article
Publicado: Elsevier B.V. Jan2015
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Does diffusion MRI tell us anything about the white matter? An overview of methods and pitfalls.
      aug:
        au:
          O'Donnell, Lauren J
          Pasternak, Ofer
      sug:
        subj:
          Research, Medical Equipment and Supplies
          Research, Medical Methods
          Magnetic Resonance Imaging
          Nerve Fibers
          Brain Anatomy and Histology
          Algorithms
          Models, Biological
      ab: One key pitfall in diffusion magnetic resonance imaging (dMRI) clinical neuroimaging research is the challenge of understanding and interpreting the results of a complex analysis pipeline. The sophisticated algorithms employed by the analysis software, combined with the relatively non-specific nature of many diffusion measurements, lead to challenges in interpretation of the results. This paper is aimed at an intended audience of clinical researchers who are learning about dMRI or trying to interpret dMRI results, and who may be wondering "Does dMRI tell us anything about the white matter?" We present a critical review of dMRI methods and measures used in clinical neuroimaging research, focusing on the most commonly used analysis methods and the most commonly reported measures. We describe important pitfalls in every section, and provide extensive references for the reader interested in more detail.
      pubtype: Academic Journal
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        Journal Article
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    language: English
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