Insomnia, hypnotic use, and health-related quality of life in a nationally representative sample.
Purpose: To assess health-related quality of life (HRQoL) associated with insomnia and prescription hypnotic use.Methods: Primary outcomes were mental component summary (MCS) and physical component summary (PCS) scores from the 12-item Short-Form Health Survey. Using multiple regression, subjects in...
| Publicado en: | Quality of Life Research Vol. 24; no. 5; pp. 1223 - 1234 |
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| Autores principales: | , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
May2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109782084&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109782084 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09629343 GPQ jtl: Quality of Life Research issn: 09629343 maglogo: N pubinfo: dt: May2015 vid: 24 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109782084 NLM25432884 2012976949 10.1007/s11136-014-0842-1 NLM25432884 109782084 ppf: 1223 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Insomnia, hypnotic use, and health-related quality of life in a nationally representative sample. aug: au: Scalo, Julieta Desai, Pooja Rascati, Karen sug: subj: Hypnotics and Sedatives Therapeutic Use Insomnia Drug Therapy Insomnia Psychosocial Factors Quality of Life Sleep Drug Effects Adult Aged Antianxiety Agents, Benzodiazepine Therapeutic Use Clinical Assessment Tools Female GABA Agonists Therapeutic Use Health Status Human Male Middle Age Prescriptions, Drug Questionnaires Retrospective Design Sleep Physiology Social Class Surveys Scales Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Purpose: To assess health-related quality of life (HRQoL) associated with insomnia and prescription hypnotic use.Methods: Primary outcomes were mental component summary (MCS) and physical component summary (PCS) scores from the 12-item Short-Form Health Survey. Using multiple regression, subjects in the 2005 through 2009 Medical Expenditure Panel Survey with diagnosed insomnia were compared against those without that diagnosis. Among subjects with diagnosed insomnia, users of prescription hypnotics were compared against nonusers.Results: Of 104,274 adults, 1.3 % (n = 1,401) had an insomnia diagnosis. Of those, 45.6 % (n = 639) used prescription hypnotics. For subjects with insomnia, mean PCS and MCS scores were 9.2 and 7.0 points lower (p < 0.001), respectively. After controlling for demographic and clinical covariates, differences remained significant (PCS:5.1;Mcs: 6.2; p < 0.001). Among subjects with insomnia, HRQoL scores were not different between prescription hypnotic users (n = 639) and nonusers (n = 762). Analysis by drug class revealed lower PCS scores (difference: 7.5, p < 0.001) with benzodiazepine use (n = 129) versus benzodiazepine receptor agonist use (n = 493), but the adjusted difference was not significant (difference: 3.8, p = .018).Conclusions: Diagnosed insomnia was associated with consistent decreases in both physical and mental HRQoL scores, regardless of whether prescription hypnotics were used. Benzodiazepine use may be associated with a further decrease in physical HRQoL scores. Although limited by its retrospective design, this study provides a first look at real-world hypnotic use outcomes at a national level. Important next steps include studies with patients serving as their own controls, and further evaluation of the sensitivity of HRQoL instruments to the effects of insomnia treatments. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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