Estimating the population distribution of usual 24-hour sodium excretion from timed urine void specimens using a statistical approach accounting for correlated measurement errors.

Background: High US sodium intake and national reduction efforts necessitate developing a feasible and valid monitoring method across the distribution of low-to-high sodium intake.Objective: We examined a statistical approach using timed urine voids to estimate the population distribution of usual 2...

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Publicado en:Journal of Nutrition Vol. 145; no. 5; pp. 1017 - 1025
Autores principales: Wang, Chia-Yih, Carriquiry, Alicia L, Chen, Te-Ching, Loria, Catherine M, Pfeiffer, Christine M, Liu, Kiang, Sempos, Christopher T, Perrine, Cria G, Cogswell, Mary E
Formato: research randomized controlled trial Journal Article
Publicado: Elsevier B.V. May2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2015
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        atl: Estimating the population distribution of usual 24-hour sodium excretion from timed urine void specimens using a statistical approach accounting for correlated measurement errors.
      aug:
        au:
          Wang, Chia-Yih
          Carriquiry, Alicia L
          Chen, Te-Ching
          Loria, Catherine M
          Pfeiffer, Christine M
          Liu, Kiang
          Sempos, Christopher T
          Perrine, Cria G
          Cogswell, Mary E
        affil: Division of Health and Nutrition Examination Surveys, National Center for Health Statistics, CDC, Hyattsville, MD; cwang@cdc.gov.
      sug:
        subj:
          Models, Biological
          Sodium Urine
          Sodium, Dietary Administration and Dosage
          Urinary Tract Physiology
          Adolescence
          Adult
          Algorithms
          Calibration
          Circadian Rhythm
          District of Columbia
          Female
          Human
          Male
          Nutritional Assessment
          Reproducibility of Results
          Reproduction
          Sodium, Dietary Metabolism
          Urban Health
          Young Adult
          Adolescent: 13-18 years
          Adult: 19-44 years
          Female
          Male
      ab: Background: High US sodium intake and national reduction efforts necessitate developing a feasible and valid monitoring method across the distribution of low-to-high sodium intake.Objective: We examined a statistical approach using timed urine voids to estimate the population distribution of usual 24-h sodium excretion.Methods: A sample of 407 adults, aged 18-39 y (54% female, 48% black), collected each void in a separate container for 24 h; 133 repeated the procedure 4-11 d later. Four timed voids (morning, afternoon, evening, overnight) were selected from each 24-h collection. We developed gender-specific equations to calibrate total sodium excreted in each of the one-void (e.g., morning) and combined two-void (e.g., morning + afternoon) urines to 24-h sodium excretion. The calibrated sodium excretions were used to estimate the population distribution of usual 24-h sodium excretion. Participants were then randomly assigned to modeling (n = 160) or validation (n = 247) groups to examine the bias in estimated population percentiles.Results: Median bias in predicting selected percentiles (5th, 25th, 50th, 75th, 95th) of usual 24-h sodium excretion with one-void urines ranged from -367 to 284 mg (-7.7 to 12.2% of the observed usual excretions) for men and -604 to 486 mg (-14.6 to 23.7%) for women, and with two-void urines from -338 to 263 mg (-6.9 to 10.4%) and -166 to 153 mg (-4.1 to 8.1%), respectively. Four of the 6 two-void urine combinations produced no significant bias in predicting selected percentiles.Conclusions: Our approach to estimate the population usual 24-h sodium excretion, which uses calibrated timed-void sodium to account for day-to-day variation and covariance between measurement errors, produced percentile estimates with relatively low biases across low-to-high sodium excretions. This may provide a low-burden, low-cost alternative to 24-h collections in monitoring population sodium intake among healthy young adults and merits further investigation in other population subgroups.
      pubtype: Academic Journal
      doctype:
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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