Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE).

An increasing recognition has emerged of the complexities of the global health agenda—specifically, the collision of infections and noncommunicable diseases and the dual burden of over- and undernutrition. Of particular practical concern are both 1) the need for a better understanding of the bidirec...

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Published in:Journal of Nutrition Vol. 145; no. 5; pp. 1039S - 1040
Main Authors: Raiten, Daniel J, Ashour, Fayrouz A Sakr, Ross, A Catharine, Meydani, Simin N, Dawson, Harry D, Stephensen, Charles B, Brabin, Bernard J, Suchdev, Parminder S, van Ommen, Ben, Sakr Ashour, Fayrouz A
Format: review Journal Article
Published: Elsevier B.V. May2015
Online Access:View this record in EBSCOhost
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      pub: Elsevier B.V.
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        atl: Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE).
      aug:
        au:
          Raiten, Daniel J
          Ashour, Fayrouz A Sakr
          Ross, A Catharine
          Meydani, Simin N
          Dawson, Harry D
          Stephensen, Charles B
          Brabin, Bernard J
          Suchdev, Parminder S
          van Ommen, Ben
          Sakr Ashour, Fayrouz A
        affil: Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD
      sug:
        subj:
          Research, Medical Methods
          Congresses and Conferences
          Diet Adverse Effects
          Medical Practice, Evidence-Based
          World Health
          Immunologic Techniques
          Nutrition
          Animals
          Biological Markers Blood
          Biological Markers Metabolism
          Research, Medical Trends
          Food Technology
          Inflammation Mediators Blood
          Inflammation Mediators Metabolism
          Nutrition Policy
          Nomenclature
      ab: An increasing recognition has emerged of the complexities of the global health agenda—specifically, the collision of infections and noncommunicable diseases and the dual burden of over- and undernutrition. Of particular practical concern are both 1) the need for a better understanding of the bidirectional relations between nutritional status and the development and function of the immune and inflammatory response and 2) the specific impact of the inflammatory response on the selection, use, and interpretation of nutrient biomarkers. The goal of the Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE) is to provide guidance for those users represented by the global food and nutrition enterprise. These include researchers (bench and clinical), clinicians providing care/treatment, those developing and evaluating programs/interventions at scale, and those responsible for generating evidence-based policy. The INSPIRE process included convening 5 thematic working groups (WGs) charged with developing summary reports around the following issues: 1) basic overview of the interactions between nutrition, immune function, and the inflammatory response; 2) examination of the evidence regarding the impact of nutrition on immune function and inflammation; 3) evaluation of the impact of inflammation and clinical conditions (acute and chronic) on nutrition; 4) examination of existing and potential new approaches to account for the impact of inflammation on biomarker interpretation and use; and 5) the presentation of new approaches to the study of these relations. Each WG was tasked with synthesizing a summary of the evidence for each of these topics and delineating the remaining gaps in our knowledge. This review consists of a summary of the INSPIRE workshop and the WG deliberations.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
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