Mother-Child Interaction as a Window to a Unique Social Phenotype in 22q11.2 Deletion Syndrome and in Williams Syndrome.

Mother-child interactions in 22q11.2 Deletion syndrome (22q11.2DS) and Williams syndrome (WS) were coded for maternal sensitivity/intrusiveness, child's expression of affect, levels of engagement, and dyadic reciprocity. WS children were found to express more positive emotions towards their mothers...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 45; no. 8; pp. 2567 - 2578
Autores principales: Weisman, Omri, Feldman, Ruth, Burg-Malki, Merav, Keren, Miri, Geva, Ronny, Diesendruck, Gil, Gothelf, Doron
Formato: research tables/charts Journal Article
Publicado: Springer Nature Aug2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2015
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      pub: Springer Nature
      place: New York, New York
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        atl: Mother-Child Interaction as a Window to a Unique Social Phenotype in 22q11.2 Deletion Syndrome and in Williams Syndrome.
      aug:
        au:
          Weisman, Omri
          Feldman, Ruth
          Burg-Malki, Merav
          Keren, Miri
          Geva, Ronny
          Diesendruck, Gil
          Gothelf, Doron
        affil: Yale Child Study Center, School of Medicine, New Haven 06519 USA
      sug:
        subj:
          22q11 Deletion Syndrome Familial and Genetic
          Williams Syndrome Familial and Genetic
          Mother-Child Relations Evaluation
          Human
          Phenotype
          Social Behavior
          Emotions
          Maternal Behavior
          Child
          Adolescence
          Female
          Male
          Adult
          Middle Age
          Checklists
          Israel
          Analysis of Variance
          Cognition
          Intelligence Tests
          Child Behavior Checklist
          Scales
          Coding
          Genotype
          Chi Square Test
          Multivariate Analysis of Covariance
          Linear Regression
          Post Hoc Analysis
          Correlation Coefficient
          T-Tests
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Mother-child interactions in 22q11.2 Deletion syndrome (22q11.2DS) and Williams syndrome (WS) were coded for maternal sensitivity/intrusiveness, child's expression of affect, levels of engagement, and dyadic reciprocity. WS children were found to express more positive emotions towards their mothers compared to 22q11.2DS children and those with developmental delay in a conflict interaction. During the same interaction, dyads of 22q11.2DS children were characterized by higher levels of maternal intrusiveness, lower levels of child's engagement and reduced reciprocity compared to dyads of typically developing children. Finally, 22q11.2DS children with the COMT Met allele showed less adaptive behaviors than children with the Val allele. Dyadic behaviors partially coincided with the distinct social phenotypes in these syndromes and are potential behavioral markers of psychopathological trajectory.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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