Acoustic radiation force impulse (ARFI) elastography for the noninvasive diagnosis of liver fibrosis in children.
Background: Acoustic radiation force impulse (ARFI) imaging) is correlated with histopathological findings using METAVIR and semiquantitative scoring system (SSS) criteria for liver fibrosis.Objective: To compare acoustic radiation force impulse imaging with biopsy results in the evaluation of liver...
| Publicado en: | Pediatric Radiology Vol. 43; no. 3; pp. 545 - 552 |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Mar2013
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=109855838&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 109855838 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03010449 O03 jtl: Pediatric Radiology issn: 03010449 maglogo: N pubinfo: dt: Mar2013 vid: 43 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 109855838 109855838 NLM23271404 2012086390 10.1007/s00247-012-2595-8 NLM23271404 109855838 ppf: 545 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Acoustic radiation force impulse (ARFI) elastography for the noninvasive diagnosis of liver fibrosis in children. aug: au: Hanquinet, Sylviane Rougemont, Anne-Laure Courvoisier, Delphine Rubbia-Brandt, Laura McLin, Valérie Tempia, Michela Anooshiravani, Mehrak affil: Department of Pediatric Radiology, University Hospitals Geneva, Geneva, Switzerland, sylviane.hanquinet-ginter@hcuge.ch. sug: subj: Algorithms Ultrasonography Methods Image Interpretation, Computer Assisted Methods Liver Cirrhosis Ultrasonography Adolescence Child Child, Preschool Female Human Image Enhancement Methods Infant Male Reproducibility of Results Sensitivity and Specificity Adolescent: 13-18 years Child: 6-12 years Child, Preschool: 2-5 years Infant: 1-23 months Female Male ab: Background: Acoustic radiation force impulse (ARFI) imaging) is correlated with histopathological findings using METAVIR and semiquantitative scoring system (SSS) criteria for liver fibrosis.Objective: To compare acoustic radiation force impulse imaging with biopsy results in the evaluation of liver fibrosis in children.Materials and Methods: Children with chronic liver disease and healthy children underwent acoustic radiation force impulse imaging liver measurements. ARFI gives a shear-wave velocity corresponding to tissue elasticity. In 39 children with liver disease, the values obtained were correlated with biopsy results. Receiver-operating characteristic (ROC) curves were used to determine the reliability of ARFI in estimating liver fibrosis in children.Results: ARFI mean value was 1.12 in the healthy group and 1.99 in children with chronic liver disease. ROC curves show that an ARFI cutoff of 1.34 m/s is predictive of both METAVIR and SSS scores with a sensitivity of SSS > 2:0.85; METAVIR > F0:0.82. A cutoff of 2 m/s yielded a sensitivity of 100% to detect SSS > 4 or METAVIR > F2.Conclusion: Acoustic radiation force impulse imaging is a reliable, noninvasive and rapid method to estimate moderate to severe liver fibrosis in children. It might prove useful to clinicians for fibrosis monitoring in children with liver disease and postpone the time of liver biopsy. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|