Degenerative changes of the corticospinal tract in pediatric patients showing deteriorated motor function: A diffusion tensor tractography study.

Objective: We attempted to demonstrate the corresponding degenerative changes of the affected corticospinal tract (CST) in pediatric patients with deteriorated motor function using diffusion tensor tractography (DTT). Methods: We recruited three pediatric patients (corrected age: 2, 6 and 47 months,...

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Publicado en:Developmental Neurorehabilitation Vol. 18; no. 5; pp. 290 - 296
Autores principales: Chang, Min Cheol, Jang, Sung Ho, Seo, Jeong Pyo, Lee, Eusil, Kim, Saeyoon, Won, Yu Hui, Son, Su Min
Formato: diagnostic images research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Oct2015
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Taylor & Francis Ltd
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        atl: Degenerative changes of the corticospinal tract in pediatric patients showing deteriorated motor function: A diffusion tensor tractography study.
      aug:
        au:
          Chang, Min Cheol
          Jang, Sung Ho
          Seo, Jeong Pyo
          Lee, Eusil
          Kim, Saeyoon
          Won, Yu Hui
          Son, Su Min
        affil: Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Taegu, Republic of Korea
      sug:
        subj:
          Cerebral Palsy Physiopathology
          Diagnosis, Brain
          Motor Activity
          Human
          Infant
          Child, Preschool
          Motor Neurons
          Diagnostic Imaging
          Infant: 1-23 months
          Child, Preschool: 2-5 years
      ab: Objective: We attempted to demonstrate the corresponding degenerative changes of the affected corticospinal tract (CST) in pediatric patients with deteriorated motor function using diffusion tensor tractography (DTT). Methods: We recruited three pediatric patients (corrected age: 2, 6 and 47 months, respectively) who showed impaired motor function. Results: DTT in each patient showed interruption of the CSTs of the hemisphere contralateral to the side of motor impairment. Despite motor impairment and abnormal DTT findings, none of the three patients received rehabilitative therapy. The patients (corrected age: 9, 53 and 59 months, respectively) and their parents visited our clinic again due to deterioration of motor functions. Follow-up DTT of all evaluated patients showed significant degenerative changes in the affected CSTs in accordance with the aggravation of motor impairment. Conclusion: We presented degenerative changes of the affected CSTs in pediatric patients according to the deterioration of motor function.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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