T2 mapping of CT remodelling patterns in interstitial lung disease.
Objectives: To evaluate lung T2 mapping for quantitative characterization and differentiation of ground-glass opacity (GGO), reticulation (RE) and honeycombing (HC) in usual interstitial pneumonia (UIP) and non-specific interstitial pneumonia (NSIP).Methods: Twelve patients with stable UIP or NSIP u...
| Publicado en: | European Radiology Vol. 25; no. 11; pp. 3167 - 3175 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Nov2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110164614&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 110164614 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Nov2015 vid: 25 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 110164614 110164614 NLM26037715 10.1007/s00330-015-3751-y NLM26037715 110164614 ppf: 3167 ppct: 8 formats: fmt: @attributes: type: P tig: atl: T2 mapping of CT remodelling patterns in interstitial lung disease. aug: au: Buzan, Maria Eichinger, Monika Kreuter, Michael Kauczor, Hans-Ulrich Herth, Felix Warth, Arne Pop, Carmen Heussel, Claus Dinkel, Julien Buzan, Maria T A Herth, Felix J Pop, Carmen Monica Heussel, Claus Peter affil: Department of Pneumology, Iuliu Hatieganu University of Medicine and Pharmacy, Hasdeu Str. 6 400371 Cluj-Napoca Romania sug: subj: Multidetector Computed Tomography Methods Respiratory Tract Physiology Physiology Magnetic Resonance Imaging Methods Lung Diseases, Interstitial Radiography Diagnostic Imaging Methods Cross Sectional Studies Image Processing, Computer Assisted Methods Idiopathic Pulmonary Fibrosis Radiography Prospective Studies Disease Progression Lung Radiography Idiopathic Pulmonary Fibrosis Diagnosis Middle Age Male Breath Holding Female Aged Aged, 80 and Over Lung Diseases, Interstitial Diagnosis Electrocardiography Methods Lung Pathology Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Objectives: To evaluate lung T2 mapping for quantitative characterization and differentiation of ground-glass opacity (GGO), reticulation (RE) and honeycombing (HC) in usual interstitial pneumonia (UIP) and non-specific interstitial pneumonia (NSIP).Methods: Twelve patients with stable UIP or NSIP underwent thin-section multislice CT and 1.5-T MRI of the lung. A total of 188 regions were classified at CT into normal (n = 29) and pathological areas, including GGO (n = 48), RE (n = 60) and HC (n = 51) predominant lesions. Entire lung T2 maps based on multi-echo single shot TSE sequence (TE: 20, 40, 79, 140, 179 ms) were generated from each subject with breath-holds at end-expiration and ECG-triggering.Results: The median T2 relaxation of GGO was 67 ms (range 60-72 ms). RE predominant lesions had a median relaxation of 74 ms (range 69-79 ms), while for HC pattern this was 79 ms (range 74-89 ms). The median T2 relaxation for normal lung areas was 41 ms (ranged 38-49 ms), and showed significant difference to pathological areas (p < 0.001). A statistical difference was found between the T2 relaxation of GGO, RE and HC (p < 0.05).Conclusions: The proposed method provides quantitative information for pattern differentiation, potentially allowing for monitoring of progression and response to treatment, in interstitial lung disease.Key Points: • Multi-echo single shot TSE sequence allows for entire lung T2 mapping. • Lung remodelling patterns in ILD show different T2 relaxation. • Quantitative T2 mapping may provide information for monitoring of ILD. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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