Ketamine induces a robust whole-brain connectivity pattern that can be differentially modulated by drugs of different mechanism and clinical profile.

Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, has been studied in relation to the glutamate hypothesis of schizophrenia and increases dissociation, positive and negative symptom ratings. Ketamine effects brain function through changes in brain activity; these activity patterns can b...

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Bibliographic Details
Published in:Psychopharmacology Vol. 232; no. 21/22; pp. 4205 - 4219
Main Authors: Joules, R., Doyle, O., Schwarz, A., O'Daly, O., Brammer, M., Williams, S., Mehta, M.
Format: Journal Article
Published: Springer Nature Nov2015
Online Access:View this record in EBSCOhost