PCP-based mice models of schizophrenia: differential behavioral, neurochemical and cellular effects of acute and subchronic treatments.
Rationale: N-methyl-D-aspartate receptor (NMDA-R) hypofunction has been proposed to account for the pathophysiology of schizophrenia. Thus, NMDA-R blockade has been used to model schizophrenia in experimental animals. Acute and repeated treatments have been successfully tested; however, long-term ex...
| Published in: | Psychopharmacology Vol. 232; no. 21/22; pp. 4085 - 4098 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Nov2015
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| Online Access: | View this record in EBSCOhost |