Part 2: Treatments for Chronic Gastrointestinal Disease and Gut Dysbiosis.

Part 1 of this review discussed the connection between the human gut microbiota and health. Manipulation of the intestinal microbiota holds promise as a prospective therapy for gut dysbiosis, ameliorating symptoms of gastrointestinal and systemic diseases and restoring health. The concept of probiot...

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Publicado en:Integrative Medicine: A Clinician's Journal Vol. 14; no. 1; pp. 25 - 34
Autores principales: Bull, Matthew J., Plummer, Nigel T.
Formato: pictorial review Journal Article
Publicado: InnoVisions Professional Media Feb2015
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Part 2: Treatments for Chronic Gastrointestinal Disease and Gut Dysbiosis.
      aug:
        au:
          Bull, Matthew J.
          Plummer, Nigel T.
        affil: Postdoctoral research associate in the Organisms and Environment Division at Cardiff University in Wales, United Kingdom
      sug:
        subj:
          Gastrointestinal Diseases Diet Therapy
          Gastrointestinal System Microbiology
          Gastrointestinal Diseases Drug Therapy
          Prebiotics Administration and Dosage
          Probiotics Administration and Dosage
          Antibiotics Administration and Dosage
          Feces Transplantation
          Probiotics Pharmacodynamics
          Prebiotics Pharmacodynamics
          Probiotics History
          Antibiotics Adverse Effects
          Diarrhea
          Dermatitis, Atopic Diet Therapy
          Inflammatory Bowel Diseases Diet Therapy
          Irritable Bowel Syndrome Diet Therapy
          Enterocolitis, Necrotizing Diet Therapy
          Metabolic Diseases Diet Therapy
      ab: Part 1 of this review discussed the connection between the human gut microbiota and health. Manipulation of the intestinal microbiota holds promise as a prospective therapy for gut dysbiosis, ameliorating symptoms of gastrointestinal and systemic diseases and restoring health. The concept of probiotics has existed for more than 100 y, and modern research methods have established sound scientific support for the perceived benefits of probiotic bacteria, which mainly include Lactobacillus and Bifidobacterium genera. On the basis of these evidence-based functional approaches, dietary interventions that supplement the normal diet with probiotics or prebiotics are now considered as potentially viable alternatives or adjuncts to the use of steroids, immunosuppressants, and/or surgical interventions. Studies investigating the impact on gastrointestinal disorders, such as diarrhea, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS); and systemic metabolic diseases, such as type 2 diabetes and obesity, in response to the use of probiotics and prebiotics are reviewed. Further, fecal microbial transplantation (FMT) is discussed as an exciting development in the treatment of gut dysbiosis using microbes.
      pubtype: Academic Journal
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        pictorial
        review
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      ougenre: Article
    language: English
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