Developments in Screening Tests and Strategies for Colorectal Cancer.

Background. Worldwide, colorectal cancer (CRC) is the third most common cancer in men and second most common in women. It is the fourth most common cause of cancer mortality. In the United States, CRC is the third most common cause of cancer and second most common cause of cancer mortality. Incidenc...

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Published in:BioMed Research International Vol. 2015; pp. 1 - 12
Main Authors: Sovich, Justin L., Sartor, Zachary, Misra, Subhasis
Format: Journal Article
Published: Wiley-Blackwell 10/4/2015
Online Access:View this record in EBSCOhost
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      dt: 10/4/2015
      vid: 2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2015/326728
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        atl: Developments in Screening Tests and Strategies for Colorectal Cancer.
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        au:
          Sovich, Justin L.
          Sartor, Zachary
          Misra, Subhasis
        affil: School of Medicine, Texas Tech University Health Sciences Center, 1400 S. Coulter Street, Amarillo, TX 79106, USA
      sug:
      ab: Background. Worldwide, colorectal cancer (CRC) is the third most common cancer in men and second most common in women. It is the fourth most common cause of cancer mortality. In the United States, CRC is the third most common cause of cancer and second most common cause of cancer mortality. Incidence and mortality rates have steadily fallen, primarily due to widespread screening. Methods. We conducted keyword searches on PubMed in four categories of CRC screening: stool, endoscopic, radiologic, and serum, as well as news searches in Medscape and Google News. Results. Colonoscopy is the gold standard for CRC screening and the most common method in the United States. Technological improvements continue to be made, including the promising "third-eye retroscope." Fecal occult blood remains widely used, particularly outside the United States. The first at-home screen, a fecal DNA screen, has also recently been approved. Radiological methods are effective but seldom used due to cost and other factors. Serum tests are largely experimental, although at least one is moving closer to market. Conclusions. Colonoscopy is likely to remain the most popular screening modality for the immediate future, although its shortcomings will continue to spur innovation in a variety of modalities.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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