Lack of ethnic differences in the pharmacokinetics and pharmacodynamics of inclacumab in healthy Japanese and Caucasian subjects.

Purpose: Inclacumab, a novel monoclonal antibody against P-selectin, is in development for the treatment and prevention of atherosclerotic cardiovascular diseases. This study was conducted to investigate potential differences in the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (...

Descripción completa

Detalles Bibliográficos
Publicado en:European Journal of Clinical Pharmacology Vol. 71; no. 11; pp. 1365 - 1375
Autores principales: Morrison, Mary, Palermo, Guiseppe, Schmitt, Christophe
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Nov2015
Acceso en línea:Ver este registro en EBSCOhost