Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease.

There are no cures for neurodegenerative diseases and this is partially due to the difficulty of monitoring pathogenic molecules in patients during life. The Parkinson's disease gene α-synuclein (SNCA) is selectively expressed in blood cells and neurons. Here we show that SNCA transcripts in circula...

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Publicado en:	Brain: A Journal of Neurology Vol. 138; no. 9; pp. 2659 - 2672
Autores principales:	Locascio, Joseph J, Eberly, Shirley, Liao, Zhixiang, Liu, Ganqiang, Hoesing, Ashley N, Duong, Karen, Trisini-Lipsanopoulos, Ana, Dhima, Kaltra, Hung, Albert Y, Flaherty, Alice W, Schwarzschild, Michael A, Hayes, Michael T, Wills, Anne-Marie, Shivraj Sohur, U, Mejia, Nicte I, Selkoe, Dennis J, Oakes, David, Shoulson, Ira, Dong, Xianjun, Marek, Ken
Formato:	research Journal Article
Publicado:	Oxford University Press / USA Sep2015
Acceso en línea:	Ver este registro en EBSCOhost