The derivation of the spatial QRS-T angle and the spatial ventricular gradient using the Mason-Likar 12-lead electrocardiogram.

Research has shown that the 'spatial QRS-T angle' (SA) and the 'spatial ventricular gradient' (SVG) have clinical value in a number of different applications. The determination of the SA and the SVG requires vectorcardiographic data. Such data is seldom recorded in clinical practice. The SA and the...

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Published in:Journal of Electrocardiology Vol. 48; no. 6; pp. 1045 - 1053
Main Authors: Guldenring, Daniel, Finlay, Dewar D., Bond, Raymond R., Kennedy, Alan, McLaughlin, James, Galeotti, Loriano, Strauss, David G.
Format: research Journal Article
Published: W B Saunders Nov/Dec2015
Online Access:View this record in EBSCOhost
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      jtl: Journal of Electrocardiology
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      dt: Nov/Dec2015
      vid: 48
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      pub: W B Saunders
      place: Philadelphia, Pennsylvania
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        10.1016/j.jelectrocard.2015.08.009
        NLM26381798
        110532627
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        atl: The derivation of the spatial QRS-T angle and the spatial ventricular gradient using the Mason-Likar 12-lead electrocardiogram.
      aug:
        au:
          Guldenring, Daniel
          Finlay, Dewar D.
          Bond, Raymond R.
          Kennedy, Alan
          McLaughlin, James
          Galeotti, Loriano
          Strauss, David G.
        affil: Ulster University, Belfast, United Kingdom
      sug:
        subj:
          Arrhythmia Diagnosis
          Arrhythmia Physiopathology
          Diagnosis, Computer Assisted Methods
          Heart Conduction System Physiopathology
          Heart Ventricle Physiopathology
          Body Surface Potential Mapping Methods
          Statistics Methods
          Reproducibility of Results
          Models, Biological
          Sensitivity and Specificity
          Computer Simulation
          Human
      ab: Research has shown that the 'spatial QRS-T angle' (SA) and the 'spatial ventricular gradient' (SVG) have clinical value in a number of different applications. The determination of the SA and the SVG requires vectorcardiographic data. Such data is seldom recorded in clinical practice. The SA and the SVG are therefore frequently derived from 12-lead electrocardiogram (ECG) data using linear lead transformation matrices. This research compares the performance of two previously published linear lead transformation matrices (Kors and ML2VCG) in deriving the SA and the SVG from Mason-Likar (ML) 12-lead ECG data. This comparison was performed through an analysis of the estimation errors that are made when deriving the SA and the SVG for all 181 subjects in the study population. The estimation errors were quantified as the systematic error (mean difference) and the random error (span of the Bland-Altman 95% limits of agreement). The random error was found to be the dominating error component for both the Kors and the ML2VCG matrix. The random error [ML2VCG; Kors; result of the paired, two-sided Pitman-Morgan test for statistical significance of differences in the error variance between ML2VCG and Kors] for the vectorcardiographic parameters SA, magnitude of the SVG, elevation of the SVG and azimuth of the SVG were found to be [37.33°; 50.52°; p<0.001], [30.17mVms; 39.09mVms; p<0.001], [36.77°; 47.62°; p=0.001] and [63.45°; 80.32°; p<0.001] respectively. The findings of this research indicate that in comparison to the Kors matrix the ML2VCG provides greater precision for estimating the SA and SVG from ML 12-lead ECG data.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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