An IMRT/VMAT Technique for Nonsmall Cell Lung Cancer.

The study is to investigate a Hybrid IMRT/VMAT technique which combines intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) for the treatment of nonsmall cell lung cancer (NSCLC). Two partial arcs VMAT, 5-field IMRT, and hybrid plans were created for 15 patients...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 8
Autores principales: Zhao, Nan, Yang, Ruijie, Wang, Junjie, Zhang, Xile, Li, Jinna
Formato: Journal Article
Publicado: Wiley-Blackwell 10/11/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 10/11/2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        110561927
        10.1155/2015/613060
        110561927
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        atl: An IMRT/VMAT Technique for Nonsmall Cell Lung Cancer.
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        au:
          Zhao, Nan
          Yang, Ruijie
          Wang, Junjie
          Zhang, Xile
          Li, Jinna
        affil: Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China
      sug:
      ab: The study is to investigate a Hybrid IMRT/VMAT technique which combines intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) for the treatment of nonsmall cell lung cancer (NSCLC). Two partial arcs VMAT, 5-field IMRT, and hybrid plans were created for 15 patients with NSCLC. The hybrid plans were combination of 2 partial arcs VMAT and 5-field IMRT. The dose distribution of planning target volume (PTV) and organs at risk (OARs) for hybrid technique was compared with IMRT and VMAT. The monitor units (MUs) and treatment delivery time were also evaluated. Hybrid technique significantly improved the target conformity and homogeneity compared with IMRT and VMAT. The mean delivery time of IMRT, VMAT, and hybrid plans was 280 s, 114 s, and 327 s, respectively. The mean MUs needed for IMRT, VMAT, and hybrid plans were 933, 512, and 737, respectively. Hybrid technique reduced V5, V10, V30, and MLD of normal lung compared with VMAT and spared the OARs better with fewer MUs with the cost of a little higher V5, V10, and mean lung dose (MLD) of normal lung compared with IMRT. Hybrid IMRT/VMAT can be a viable radiotherapy technique with better plan quality.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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