Accuracy of Echocardiographic Cardiac Index Assessment in Subjects with Preserved Left Ventricular Ejection Fraction.

Introduction We aimed to determine the accuracy of the echocardiographic assessment of cardiac index ( CI) in subjects with preserved left ventricular ejection fraction ( LVEF). Methods Thirty-three subjects with LVEF >50%, normal sinus rhythm, and a broad spectrum of hemodynamic profiles underwent...

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Publicado en:Echocardiography Vol. 32; no. 11; pp. 1628 - 1639
Autores principales: Maeder, Micha T., Karapanagiotidis, Sofie, Dewar, Elizabeth M., Kaye, David M.
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2015
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Accuracy of Echocardiographic Cardiac Index Assessment in Subjects with Preserved Left Ventricular Ejection Fraction.
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          Maeder, Micha T.
          Karapanagiotidis, Sofie
          Dewar, Elizabeth M.
          Kaye, David M.
        affil: Heart Failure Research Group, Baker IDI Heart and Diabetes Institute, Melbourne Victoria, Australia
      sug:
        subj:
          Hemodynamics
          Ventricular Ejection Fraction
          Ventricular Function, Left Evaluation
          Echocardiography Utilization
          Cardiac Output Determination
          Echocardiography Methods
          Thermodilution Utilization
          Prospective Studies
          Heart Catheterization
          Inpatients
          Invasive Procedures
          Noninvasive Procedures
          Descriptive Statistics
          Data Analysis Software
          P-Value
          Chi Square Test
          One-Way Analysis of Variance
          Kruskal-Wallis Test
          T-Tests
          Post Hoc Analysis
          Pearson's Correlation Coefficient
          Pulmonary Arterial Hypertension
          Heart Failure
          Cardiac Patients Classification
          Stroke Volume
          Human
          Female
          Male
          Adult
          Middle Age
          Aged
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: Introduction We aimed to determine the accuracy of the echocardiographic assessment of cardiac index ( CI) in subjects with preserved left ventricular ejection fraction ( LVEF). Methods Thirty-three subjects with LVEF >50%, normal sinus rhythm, and a broad spectrum of hemodynamic profiles underwent echocardiography immediately followed by right heart catheterization. As gold standards, CI was assessed using thermodilution [ CI ( TD)] and the Fick method [ CI (F)]. Echocardiographic CI was assessed by four methods: from the left ventricular outflow tract ( LVOT) velocity time integral and the LVOT diameter as measured [ CI ( LVOTm)] as well as estimated from body surface area [ CI ( LVOTe)], and from stroke volume indices assessed using the biplane [ CI ( BP)] and monoplane [ CI ( MP)] methods. Results The mean CI ( TD), CI (F), CI ( LVOTm), CI ( LVOTe), CI ( BP), and CI ( MP) were 3.0 ± 0.9, 3.1 ± 0.7, 2.8 ± 0.6, 3.3 ± 0.6, 2.0 ± 0.6, and 2.2 ± 0.7 L/min/m2. There were modest correlations between CI ( TD) and CI (F) and all four noninvasive measures of CI with r2 values ranging from 0.09 to 0.30. CI ( LVOTm) underestimated CI ( TD) and CI (F) by 0.3 and 0.3 L/min/m2, CI ( LVOTe) overestimated CI ( TD) and CI (F) by 0.3 and 0.2 L/min/m2, and CI ( BP) and CI ( MP) underestimated CI ( TD) and CI (F) by 1.1 and 1.1 L/min/m2 and 0.9 and 0.9 L/min/m2, respectively, with large limits of agreement for all comparisons. Conclusions In subjects with nondilated left ventricles with preserved LVEF, flow- or volume-based measures of CI by 2D echocardiography may not accurately reflect CI ( TD) and CI (F). Further larger studies are required to verify our findings and to evaluate the accuracy of contrast and 3D echocardiography in this setting.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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