IgY antibodies in human nutrition for disease prevention.
Oral administration of preformed specific antibodies is an attractive approach against infections of the digestive system in humans and animals in times of increasing antibiotic resistances. Previous studies showed a positive effect of egg yolk IgY antibodies on bacterial intoxications in animals an...
| Publicado en: | Nutrition Journal Vol. 14; pp. 1 - 8 |
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| Autores principales: | , , , , |
| Formato: | review tables/charts Journal Article |
| Publicado: |
BioMed Central
10/20/2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110615440&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 110615440 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14752891 1CYY jtl: Nutrition Journal issn: 14752891 maglogo: N pubinfo: dt: 10/20/2015 vid: 14 pid: 24147 pub: BioMed Central artinfo: ui: 110615440 110615440 NLM26487372 110615440 10.1186/s12937-015-0067-3 NLM26487372 PMC4617726 110615440 ppf: 1 ppct: 7 formats: fmt: @attributes: type: P tig: atl: IgY antibodies in human nutrition for disease prevention. aug: au: Müller, Sandra Schubert, Andreas Zajac, Julia Dyck, Terry Oelkrug, Christopher affil: Fraunhofer Institute for Cell Therapy and Immunology (IZI), Perlickstraße 1, 04103 Leipzig, Germany sug: subj: Eggs Digestive System Diseases Prevention and Control Immunoglobulins Therapeutic Use Digestive System Diseases Immunology Immunoglobulins Immunology Antibodies Therapeutic Use Antibodies Immunology ab: Oral administration of preformed specific antibodies is an attractive approach against infections of the digestive system in humans and animals in times of increasing antibiotic resistances. Previous studies showed a positive effect of egg yolk IgY antibodies on bacterial intoxications in animals and humans. Immunization of chickens with specific antigens offers the possibility to create various forms of antibodies. Research shows that orally applied IgY's isolated from egg yolks can passively cure or prevent diseases of the digestive system. The use of these alternative therapeutic drugs provides further advantages: (1) The production of IgY's is a non-invasive alternative to current methods; (2) The keeping of chickens is inexpensive; (3) The animals are easy to handle; (4) It avoids repetitive bleeding of laboratory animals; (5) It is also very cost effective regarding the high IgY concentration within the egg yolk. Novel targets of these antigen specific antibodies are Helicobacter pylori and also molecules involved in signaling pathways in gastric cancer. Furthermore, also dental caries causing bacteria like Streptococcus mutans or opportunistic Pseudomonas aeruginosa in cystic fibrosis patients are possible targets. Therefore, IgY's included in food for human consumption may be able to prevent or cure human diseases. pubtype: Academic Journal doctype: review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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