Affective processing bias in youth with primary bipolar disorder or primary attention-deficit/hyperactivity disorder.
High rates of comorbidity and overlapping diagnostic criteria between pediatric bipolar disorder (BD) and attention-deficit/hyperactivity disorder (ADHD) contribute to diagnostic and treatment confusion. To advance what is known about both disorders, we compared effect of emotional stimuli on respon...
| Publicado en: | European Child & Adolescent Psychiatry Vol. 24; no. 11; pp. 1349 - 1360 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Nov2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110653074&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 110653074 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: Nov2015 vid: 24 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 110653074 110653074 110653074 10.1007/s00787-015-0686-4 NLM25724546 110653074 ppf: 1349 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Affective processing bias in youth with primary bipolar disorder or primary attention-deficit/hyperactivity disorder. aug: au: Seymour, Karen Kim, Kerri Cushman, Grace Puzia, Megan Weissman, Alexandra Galvan, Thania Dickstein, Daniel affil: Divison of Child and Adolescent Psychiatry, Johns Hopkins University School of Medicine, 550 North Broadway Street, Suite 943 Baltimore 21205 USA sug: subj: Bipolar Disorder Diagnosis Attention Deficit Hyperactivity Disorder Diagnosis Comorbidity Trends Human Child Neuropsychological Tests Adolescence Male Female Rhode Island Task Performance and Analysis Descriptive Statistics Data Analysis Software Repeated Measures Analysis of Variance Effect Size Chi Square Test Paired T-Tests Matched-Pair Analysis Post Hoc Analysis Funding Source Child: 6-12 years Adolescent: 13-18 years Male Female ab: High rates of comorbidity and overlapping diagnostic criteria between pediatric bipolar disorder (BD) and attention-deficit/hyperactivity disorder (ADHD) contribute to diagnostic and treatment confusion. To advance what is known about both disorders, we compared effect of emotional stimuli on response control in children with primary BD, primary ADHD and typically developing controls (TDC). Participants included 7-17 year olds with either 'narrow-phenotype' pediatric BD ( n = 25), ADHD ( n = 25) or TDC ( n = 25). Groups were matched on participant age and FSIQ. The effect of emotional stimuli on response control was assessed using the Cambridge Neuropsychological Test Automated Battery Affective Go/No-Go task (CANTAB AGN). We found a group by target valence interaction on commission errors [ F(2,71) = 5.34, p < 0.01, ƞ = 0.13] whereby ADHD, but not TDC participants, made more errors on negative than positive words [ t(24) = −2.58, p < 0.05, r = 0.47]. In contrast, there was a nonsignificant trend for BD participants to make fewer errors on negative versus positive words compared to ADHD and TDC participants. Between-subjects effects showed that ADHD participants made more errors than TDC, but not BD participants. Our main finding advances what is known about the effect of emotional stimuli on response control in children with ADHD. Our results suggesting a positive affective processing bias in children with ADHD compliment emerging literature show that difficulties with emotional processing and regulation may be core features of ADHD. Further, given the observed pattern of results in children with ADHD compared to BD children, our behavioral results suggest the importance of examining differences in the brain-behavior mechanisms involved in affective processing in children with ADHD compared to BD children. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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