Pulmonary Rehabilitation in COPD: Effect of 2 Aerobic Exercise Intensities on Subject-Centered Outcomes--A Randomized Controlled Trial.

BACKGROUND: Exercise training is an important component of pulmonary rehabilitation, but it remains questionable how training intensity affects patient-centered outcomes. The aim of this study was to compare the effects of 2 aerobic training intensities on health-related quality of life (HRQOL), sym...

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Publicado en:Respiratory Care Vol. 60; no. 11; pp. 1603 - 1610
Autores principales: Santos, Catarina, Rodrigues, Fatima, Santos, Joana, Morais, Luísa, Bárbara, Cristina
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Mary Ann Liebert, Inc. Nov2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2015
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      pub: Mary Ann Liebert, Inc.
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        atl: Pulmonary Rehabilitation in COPD: Effect of 2 Aerobic Exercise Intensities on Subject-Centered Outcomes--A Randomized Controlled Trial.
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        au:
          Santos, Catarina
          Rodrigues, Fatima
          Santos, Joana
          Morais, Luísa
          Bárbara, Cristina
        affil: Fisioterapia, Centro Hospitalar de Lisboa Ocidental-Hospital de Egas Moniz, Lisbon, Portugal
      sug:
        subj:
          Rehabilitation, Pulmonary
          Pulmonary Disease, Chronic Obstructive
          Aerobic Exercises
          Outcomes (Health Care)
          Quality of Life
          Human
          Male
          Female
          P-Value
          Confidence Intervals
          Randomized Controlled Trials
          Questionnaires
          Clinical Assessment Tools
          Scales
          Exercise Test, Cardiopulmonary
          Data Analysis Software
          T-Tests
          Mann-Whitney U Test
          Pearson's Correlation Coefficient
          Spearman's Rank Correlation Coefficient
          Middle Age
          Aged
          Age Factors
          Internal Validity
          Exercise Physiology
          Health Behavior
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: BACKGROUND: Exercise training is an important component of pulmonary rehabilitation, but it remains questionable how training intensity affects patient-centered outcomes. The aim of this study was to compare the effects of 2 aerobic training intensities on health-related quality of life (HRQOL), symptom control, and exercise tolerance in subjects with COPD. METHODS: Thirty-four subjects with mild to very severe COPD participated in an equivalence/non-inferiority randomized controlled trial with a parallel group blinded to 60 or 80% maximum work rate (Wmax) aerobic training intensity. The intervention was an out-patient pulmonary rehabilitation program conducted 3 times/week for 8 weeks. Outcomes were assessed with the St George Respiratory Questionnaire (primary outcome), Mahler's dyspnea index, London Chest Activity of Daily Living scale, 6-min walk test, and constant-load and incremental exercise tests. RESULTS: Subjects were randomly allocated to aerobic training intensity of 60% Wmax (group 1, n = 17) or 80% Wmax (group 2, n = 17). Although there were significant improvements in all outcomes for both groups, there were no between-group differences in mean change in the St George Respiratory Questionnaire (P = .31, 95% Cl -12.0 to 3.9), Mahler's dyspnea index (P = .38), London Chest Activity of Daily Living scale (P = .92), 6-min walk test (P = .50, 95% Cl 6.2-71.1), constant-load exercise test (P = .50), and incremental exercise test (P = .12). There was only one exercise-related adverse event of cardiac symptoms. CONCLUSIONS: Aerobic training intensity of at least 60% Wmax has a positive impact on COPD patient-centered outcomes, with no additional benefit of increasing intensity to 80% Wmax in HRQOL, symptom control, and exercise tolerance, challenging the present clinical attitude of rehabilitation professionals.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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