Low Cognitive Ability in Subjects With Bronchiectasis.
BACKGROUND: Bronchiectasis may change cognitive function. The mechanism responsible for cognitive dysfunction in COPD may be neuronal damage caused by hypoxia. Cognitive function in patients with bronchiectasis is also likely to be affected by similar mechanisms. The goal of this study was to determ...
| Publicado en: | Respiratory Care Vol. 60; no. 11; pp. 1610 - 1616 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Nov2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110709064&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 110709064 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Nov2015 vid: 60 iid: 11 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 110709064 110709064 110709064 10.4187/respcare.03905 NLM26221045 110709064 ppf: 1610 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Low Cognitive Ability in Subjects With Bronchiectasis. aug: au: Gülhan, Pınar Yıldız Bulcun, Emel Gülhan, Mustafa Çimen, Dilay Ekici, Aydanur Ekici, Mehmet affil: Department of Pulmonary Diseases, Kırıkkale University, Kırıkkale, Turkey sug: subj: Bronchiectasis Psychosocial Factors Cognition Scales Human Dyspnea Male Female Adult Middle Age Chi Square Test Bivariate Statistics Linear Regression Pearson's Correlation Coefficient P-Value Body Mass Index Multivariate Analysis Oxygen Saturation Respiratory Function Tests T-Tests Mann-Whitney U Test Anoxemia Intelligence Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: BACKGROUND: Bronchiectasis may change cognitive function. The mechanism responsible for cognitive dysfunction in COPD may be neuronal damage caused by hypoxia. Cognitive function in patients with bronchiectasis is also likely to be affected by similar mechanisms. The goal of this study was to determine the frequency and determinants of low cognitive ability in subjects with stable bronchiectasis. METHODS: Thirty subjects with stable bronchiectasis and 25 healthy volunteers underwent a cognitive ability assessment using the Wechsler Adult Intelligence Scale. Bronchiectasis was diagnosed by high-resolution computed tomography of the chest. Age, body mass index, the Hospital Anxiety and Depression Scale, and pulmonary function were assessed. Perceived intensity of dyspnea after exercise (after climbing 3 flights of stairs) was estimated using a modified Borg scale. RESULTS: Mean scores on the verbal and performance tests and full-scale IQ scores were significantly lower in subjects with bronchiectasis than in healthy volunteers. Low cognitive ability in subjects with bronchiectasis was associated with higher depression scores, lower oxygen saturation, and poor lung function after adjusting for potential confounders in multivariate analysis. Borg scores after exercise in subjects with bronchiectasis and low cognitive ability were higher than those in subjects with bronchiectasis and high cognitive ability, despite similar ... and FEV1 in both groups. CONCLUSIONS: Low cognitive ability in subjects with bronchiectasis may be associated with reduced lung function, more serious hypoxemia, and higher depressive symptoms. Subjects with bronchiectasis and low cognitive ability feel more intense dyspnea than do those with high cognitive ability. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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