Quality of Life and Bronchial Hyper-Responsiveness in Subjects With Bronchiectasis: Validation of the Seattle Obstructive Lung Disease Questionnaire in Bronchiectasis.

BACKGROUND: Bronchiectasis can adversely affect quality of life. However, the tests examining quality of life in bronchiectasis are not sufficient. We examined the validity of a measure designed for COPD, the Seattle Obstructive Lung Disease Questionnaire (SOLQ), in bronchiectasis. In addition, we a...

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Publicado en:Respiratory Care Vol. 60; no. 11; pp. 1616 - 1624
Autores principales: Bulcun, Emel, Arslan, Mesut, Ekici, Aydanur, Ekici, Mehmet
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Nov2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2015
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      pub: Mary Ann Liebert, Inc.
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        atl: Quality of Life and Bronchial Hyper-Responsiveness in Subjects With Bronchiectasis: Validation of the Seattle Obstructive Lung Disease Questionnaire in Bronchiectasis.
      aug:
        au:
          Bulcun, Emel
          Arslan, Mesut
          Ekici, Aydanur
          Ekici, Mehmet
        affil: Department of Pulmonary Diseases, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey
      sug:
        subj:
          Instrument Validation
          Quality of Life
          Bronchiectasis Psychosocial Factors
          Questionnaires
          Coefficient alpha
          Human
          Male
          Female
          Pearson's Correlation Coefficient
          Spirometry
          Tomography, X-Ray Computed
          Test-Retest Reliability
          T-Tests
          Mann-Whitney U Test
          Linear Regression
          P-Value
          Internal Consistency
          Scales
          Severity of Illness
          Male
          Female
      ab: BACKGROUND: Bronchiectasis can adversely affect quality of life. However, the tests examining quality of life in bronchiectasis are not sufficient. We examined the validity of a measure designed for COPD, the Seattle Obstructive Lung Disease Questionnaire (SOLQ), in bronchiectasis. In addition, we aimed to compare the quality of life of subjects with bronchiectasis and bronchial hyper-responsiveness with that of those without to identify the effective factors. METHODS: We studied 78 subjects with clinically stable bronchiectasis and 41 healthy controls matched for age and sex. Subjects were assessed by the SOLQ. A detailed history, physical examination, the Medical Outcomes Study 36-Item Short Form questionnaire, the Hospital Anxiety and Depression Scale, and spirometric measurements were obtained. RESULTS: Cronbach a coefficients, which reflected internal consistency, were >0.70 for all SOLQ components except for treatment satisfaction. SOLQ component scores correlated with all of the component scores of the Medical Outcomes Study 36-Item Short Form questionnaire and the Hospital Anxiety and Depression Scale, confirming their concurrent validity. All SOLQ scores correlated positively with percent-of-predicted FEV1, whereas the physical function, treatment satisfaction, and emotional function correlated negatively with the exacerbation frequency in Pearson analysis. Emotional and physical functions were positively associated with percent-of-predicted FEV1 in linear regression analysis. Compared with subjects without bronchial hyper-responsiveness, those with bronchial hyper-responsiveness had lower FEV1/FVC and more exacerbations/y. Compared with bronchiectasis subjects without bronchial hyper-responsiveness, those with bronchial hyper-responsiveness had significantly lower SOLQ, physical function, and coping skills scores but not emotional function and treatment satisfaction. CONCLUSIONS: The SOLQ is a valid instrument for determining quality of life in subjects with bronchiectasis. Subjects with bronchiectasis and bronchial hyper-responsiveness had a poorer quality of life, lower baseline spirometric values, and more frequent exacerbations, suggesting more severe disease.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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