Adsorción de fenobarbital en carbones activados comerciales. Equilibrio cinético e isotermo de adsorción.
The in vitro adsorption of phenobarbital by different adsorbents in simulated gastric fluid (SGF) at pH 1.2 and 310 K, was determined on three types of commercial samples of activated carbon (AC): Norit USP XX, Ch3J (both used as antidotes) and M1. The equilibrium isotherms for the adsorption of phe...
| Publicado en: | Revista CENIC Ciencias Quimicas Vol. 45; no. 1; pp. 172 - 184 |
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| Autores principales: | , , , , |
| Formato: | Artículo |
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Centro Nacional de Investigaciones Cientificas
2014
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=110742408&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 110742408 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 10158553 UF0 jtl: Revista CENIC Ciencias Quimicas issn: 10158553 maglogo: N pubinfo: dt: 2014 vid: 45 iid: 1 pid: 21205 pub: Centro Nacional de Investigaciones Cientificas artinfo: ui: 110742408 ppf: 172 ppct: 12 formats: fmt: @attributes: type: P size: 2MB tig: atl: Adsorción de fenobarbital en carbones activados comerciales. Equilibrio cinético e isotermo de adsorción. aug: au: Rey-Mafull, Carlos Alberto Cesar-Llopiz, Julio Iglesias-Cerveto, Alberto Hotza, Dachamir Garcia-Gallardo, Raquel affil: Instituto de Ciencia y Tecnología de Materiales de La Universidad de la Habana (Cuba) Facultad de Física de La Universidad de la Habana (Cuba) su: Activated carbon Phenobarbital Adsorption (Chemistry) Atmospheric temperature Gastric juice Sorbents sug: subj: Activated carbon Phenobarbital Adsorption (Chemistry) Atmospheric temperature Gastric juice Sorbents keyword: activated carbon adsorption isotherms kinetic phenobarbital adsorción carbón activado cinética fenobarbital isotermas ab: The in vitro adsorption of phenobarbital by different adsorbents in simulated gastric fluid (SGF) at pH 1.2 and 310 K, was determined on three types of commercial samples of activated carbon (AC): Norit USP XX, Ch3J (both used as antidotes) and M1. The equilibrium isotherms for the adsorption of phenobarbital were analyzed by four models: Langmuir (Type I and II), D-R, Freundlich and Temkin isotherms equations and the kinetic curves obtained were fitted using seven equations (Elovich, pseudo-first order, pseudo-second order, zero order, first order, second order and the intraparticle model) to determine kinetic parameters of adsorption. The pseudo-second order and the Langmuir model respectively showed the best fittings. The pseudo-second order suggered that the overall rate of the adsorption was controlled by chemisorption which involved valency forces through sharing or exchange of electrons between the sorbent and adsorbate The correlation coefficients (R) obtained from Langmuir model for the linear regression in all cases were higher than 0.99. Kinetic studies showed that the adsorption of phenobarbital on the three adsorbents obtained the best results with the pseudo-second order model TI (R > 0.98) and TII (R ≥ 0.92) respectively. The variation of the free Gibbs energy (ΔG < 0), in all cases, explained the spontaneous character of the adsorption process. Despite the different behaviors all materials tested have potential for treating phenobarbital intoxications. La adsorcion in vitro de fenobarbital en fluido gástrico simulado (FGS), pH 1,2 y 310 K, fue estudiada a partir de tres carbones activados comerciales: Norit USP XX, Ch3J (ambos usados como antídotos) y M1. Las isotermas de adsorción correspondientes fueron analizadas por cuatro modelos: Langmuir (Tipo I y II), D-R, Freundlich y Temkin; la cinética de adsorción por siete modelos: Elovich, pseudo-primer orden, pseudo-segundo orden, orden cero, primer orden, segundo orden e intrapartícula. Los mejores ajustes en ambos casos fueron obtenidos por el modelo de monocapa de Langmuir y pseudo-segundo orden respectivamente. Este modelo cinético propone que la velocidad de adsorción está controlada por mecanismos de quimisorción entre el adsorbato y el adsorbente. El coeficiente de correlación (R) obtenido por Langmuir en todos los casos, fue superior a 0.99. El estudio cinético mostró que la adsorción de fenobarbital en los tres adsorbentes alcanzó sus mejores resultados con el modelo de pseudo-second order TI (R > 0.98) y TII (R ≥ 0.92). La variación de la energía libre de Gibbs (ΔG < 0) explica el carácter espontáneo del proceso de adsorción. Todos los materiales estudiados muestran potenciales capacidades para la adsorción de fenobarbital. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Revista CENIC Ciencias Quimicas is the property of Centro Nacional de Investigaciones Cientificas and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Revista CENIC Ciencias Quimicas holder: Centro Nacional de Investigaciones Cientificas dt: @attributes: year: 2014 holdings: @attributes: islocal: N |
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