Assessing hepatic fibrosis: comparing the intravoxel incoherent motion in MRI with acoustic radiation force impulse imaging in US.

Objectives: This study compared the diagnostic performance of intravoxel incoherent motion (IVIM) in magnetic resonance imaging (MRI) and acoustic radiation force impulse imaging (ARFI) in ultrasound (US) for liver fibrosis (LF) evaluation.Methods: A total of 49 patients scheduled for liver surgery...

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Publicado en:European Radiology Vol. 25; no. 12; pp. 3552 - 3560
Autores principales: Wu, Chih-Horng, Ho, Ming-Chih, Jeng, Yung-Ming, Liang, Po-Chin, Hu, Rey-Heng, Lai, Hong-Shiee, Shih, Tiffany, Shih, Tiffany Ting-Fang
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Dec2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2015
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      pub: Springer Nature
      place: New York, New York
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        atl: Assessing hepatic fibrosis: comparing the intravoxel incoherent motion in MRI with acoustic radiation force impulse imaging in US.
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        au:
          Wu, Chih-Horng
          Ho, Ming-Chih
          Jeng, Yung-Ming
          Liang, Po-Chin
          Hu, Rey-Heng
          Lai, Hong-Shiee
          Shih, Tiffany
          Shih, Tiffany Ting-Fang
        affil: Department of Surgery, National Taiwan University Hospital and College of Medicine, Taipei Taiwan
      sug:
        subj:
          Magnetic Resonance Imaging
          Liver Cirrhosis Pathology
          Liver Cirrhosis Ultrasonography
          Ultrasonography
          Human
          Middle Age
          Male
          Prospective Studies
          Young Adult
          Reproducibility of Results
          Liver Pathology
          ROC Curve
          Liver Ultrasonography
          Aged
          Aged, 80 and Over
          Adult
          Female
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Scales
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Adult: 19-44 years
          Male
          Female
      ab: Objectives: This study compared the diagnostic performance of intravoxel incoherent motion (IVIM) in magnetic resonance imaging (MRI) and acoustic radiation force impulse imaging (ARFI) in ultrasound (US) for liver fibrosis (LF) evaluation.Methods: A total of 49 patients scheduled for liver surgery were recruited. LF in the non-tumorous liver parenchyma at the right lobe was estimated using a slow diffusion coefficient, fast diffusion coefficient (D fast), perfusion fraction (f) of the IVIM parameters, the total apparent diffusion coefficient of conventional diffusion-weighted imaging and the shear wave velocity (Vs) of ARFI. LF was graded using the Metavir scoring system on histological examination. The Spearman rank correlation coefficient for correlation and analysis of variance was used for determining difference. The diagnostic performance was compared using receiver operating characteristic curve analysis.Results: LF exhibited significant correlation with the three parameters D fast, f, and Vs (r = -0.528, -0.337, and 0.481, respectively, P < 0.05). The D fast values in the F4 group were significantly lower than those in the F0, F1 and F2 groups. D fast exhibited a non-inferior performance for diagnosing all fibrosis grades compared with that of Vs.Conclusions: Both IVIM and ARFI provide reliable estimations for the noninvasive assessment of LF.Key Points: • Liver fibrosis can be diagnosed and graded using noninvasive imaging modalities. • ARFI and IVIM can be incorporated into routine examinations. • IVIM can differentiate liver cirrhosis from none to moderate liver fibrosis. • The diagnostic performances of IVIM and ARFI are equal.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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