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Drug-induced haemolysis, renal failure, thrombocytopenia and lactic acidosis in patients with HIV and cryptococcal meningitis: a diagnostic challenge.

Patients with HIV are at risk of both primary and secondary haematological disorders. We report two cases of patients with HIV and cryptococcal meningitis who developed severe haemolytic anaemia, thrombocytopenia, renal failure and lactic acidosis while on treatment with amphotericin B and co-trimox...

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Published in:International Journal of STD & AIDS Vol. 26; no. 14; pp. 1052 - 1055
Main Authors: Camara-Lemarroy, Carlos R., Flores-Cantu, Hazael, Calderon-Hernandez, Hector J., Diaz-Torres, Marco A., Villareal-Velazquez, Hector J.
Format: case study Journal Article
Published: Sage Publications Inc. Dec2015
Online Access:View this record in EBSCOhost
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      dt: Dec2015
      vid: 26
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Drug-induced haemolysis, renal failure, thrombocytopenia and lactic acidosis in patients with HIV and cryptococcal meningitis: a diagnostic challenge.
      aug:
        au:
          Camara-Lemarroy, Carlos R.
          Flores-Cantu, Hazael
          Calderon-Hernandez, Hector J.
          Diaz-Torres, Marco A.
          Villareal-Velazquez, Hector J.
        affil: Servicio de Neurologia, Hospital Universitario “Dr. José E. González”, Universidad Autónoma de Nuevo León, Monterrey, México
      sug:
        subj:
          Cryptococcus Drug Effects
          Antifungal Agents Therapeutic Use
          Meningitis, Cryptococcal Drug Therapy
          Anemia, Hemolytic Chemically Induced
          Renal Insufficiency Chemically Induced
          Thrombocytopenia Chemically Induced
          Acidosis, Lactic Chemically Induced
          Amphotericin B Adverse Effects
          Cryptococcus
          Adult
          Male
          Amphotericin B Administration and Dosage
          Renal Insufficiency Diagnosis
          AIDS-Related Opportunistic Infections Microbiology
          Anemia, Hemolytic Diagnosis
          Antifungal Agents Adverse Effects
          AIDS-Related Opportunistic Infections Drug Therapy
          Acidosis, Lactic Diagnosis
          Thrombocytopenia Diagnosis
          Amphotericin B Therapeutic Use
          Treatment Outcomes
          Meningitis, Cryptococcal Diagnosis
          Female
          Drug Therapy, Combination
          Adult: 19-44 years
          Male
          Female
      ab: Patients with HIV are at risk of both primary and secondary haematological disorders. We report two cases of patients with HIV and cryptococcal meningitis who developed severe haemolytic anaemia, thrombocytopenia, renal failure and lactic acidosis while on treatment with amphotericin B and co-trimoxazole.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
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